Desflurane

  • Advantages:
    • Rapid onset and recovery of anesthesia (outpatient procedures).
    • One of the least metabolized to toxic byproducts.
  • Disadvantages:
    • Requires a special vaporizer.
    • Pungent and irritating to the airway (leading to more coughing, laryngospasm).
    • High inspired gas concentrations lead to a significant ↑ in the patient’s BP & HR.