Angioedema/Anaphylaxis

Characteristics

  • Caused by degranulation of mast cells in the deeper dermis and subcutaneous tissues.
  • May occur along with urticaria (50% of cases)
  • Can be life-threatening if it causes laryngeal edema or tongue swelling.
  • Can be non-mast cell mediated, as in the case of ACE-inhibitors.