Pregnancy Dermatoses presentations
There are four specific dermatoses of pregnancy, according to the most recent proposed classification:
- Pemphigoid gestationis
- Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP)
- Intrahepatic Cholestasis of Pregnancy (ICP)
- Atopic Eruption of Pregnancy (AEP)
Dr Sami Aldaham
Each pregnancy dermatosis is distinct and carries different risks for the mother and the fetus.
A distinction must be made between dermatological diseases that happen to occur while the patient is pregnant versus specific dermatoses that occur only during pregnancy.
Pregnant patients with dermatologic conditions requiring treatment should be co-managed with an obstetrician.
Goals and Objectives
- By completing this module, the learner will be able to:
- Identify and describe the morphology of specific dermatoses of pregnancy
- List which dermatoses of pregnancy carry risks for the mother and the fetus
- Explain basic principles in the diagnosis and treatment of specific pregnancy dermatoses
PG versus PUPPP
| Pemphigoid gestationis | PUPPP | |
|---|---|---|
| ONSET | 2nd or 3rd trimester | 3rd trimester |
| BLISTERS | common | rare |
| BIOPSY/IF | diagnostic | non-diagnostic |
| FETAL RISKS | SGA, preterm, blisters | none |
| RECURRENCE | yes | no |
Going back to our cases:
Review Question 1
- Which disease is caused by specific antibodies? a. Atopic eruption of pregnancy b. Intrahepatic cholestasis of pregnancy c. Pemphigoid gestationis d. Pruritic urticarial papules and plaques of pregnancy
Review Question 1
- Which disease is caused by specific antibodies? a. Atopic eruption of pregnancy b. Intrahepatic cholestasis of pregnancy c. Pemphigoid gestationis d. Pruritic urticarial papules and plaques of pregnancy
Review Question 2
- Which of the following is true?
- Atopic eruption of pregnancy only occurs in patients with a history of atopic dermatitis.
- Intrahepatic cholestasis of pregnancy can have serious complications for both mother and child.
- PUPPP and pemphigoid gestationis have identical findings on immunofluorescence.
- There is a high risk of blisters in the neonate in pemphigoid gestationis. (although not high, very low)