PEDIA-OSPE


EEG

If 3 spikes in 1 second - petite mal epilepsy i.e. absence seizure


Hibs HYBS? arrhythmia - tubelous sclerosis y  EEG, hypsarrhythmia, infantile spasms, and tuberous sclerosis complex (TSC)  


Cerebral Palsy Types

Spastic CP (Scissoring legs):

  • Large ears
  • Muscle wasting
  • Fisting in hands (resistive hand posture)
  • Nystagmus
  • History of severe birth asphyxia

This child has a history of severe Birth Asphyxia.What are your neurological diagnoses?

  • Severe microcephaly (brain atrophy)
  • Severe spastic quadriplegic cerebral palsy

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img-3.jpeg|0x0 Case about a child who’s drooling no important data other than the drooling as far as i remember.

Q1: what’s the diagnosis? A: dyskinetic cerebral palsy.

Q2: what’s the origin? A: extrapyramidal.


Dystonic cerebral palsy or dyskinetic or choreoathetoid cerebral palsyimg-395.jpeg|218x244

Findings:

  • Involuntary muscle spasms and unwanted movement
  • Poor saliva control
  • Drooling

Origin:

  • Extrapyramidal involvement

IQ:

  • Normal

Fisting (Persistence >6-8 weeks)

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When should disappear in normal child?

  • 6-8 weeks of birth

Persistence at 12 months indicates:

  • Cerebral palsy
  • Edward syndrome

Neurology & Neonatology


MRI Findings in Hypotonia

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Modality: MRI

Findings:

  • Absent corpus callosum
  • Asymmetrical ventricles
  • Brain atrophy
  • Brain central edema

Type of Hypotonia:

  • Central hypotonia

Hypotonia Types

Central Hypotonia

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Findings:

  • Rigid joints
  • Long neck
  • Long tongue
  • Thick lips
  • Rigid joint, long neck, long tongue, thick lips
  • Central hypotonia

Diagnosis:

  • Screen for Mucopolysaccharidosis type 2 (Hunter syndrome) x-linked

Other Causes:

  • Cerebral palsy
  • Brain damage due to HIE
  • Muscular dystrophy


Axial Hypotonia

2 month old baby is examined in the clinic Tests:

  • Ventral suspension test (inverted U shape)
  • Pull to sit test (head lag)

Findings:

  • U-shaped on ventral suspension
  • Floppy child
  • Head lag on pull to sit test

Causes:

  • Down syndrome
  • Cerebral palsy
  • Muscular dystrophies

How do you expect the power?

  • Reduced.

img-95.jpeg|271x200img-107.jpeg|269x221U shaped img-108.jpeg|325x381img-111.jpeg|340x255


Peripheral Hypotonia

This is a hypotonic infant with Fasciculations in the tongue.

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Findings:

  • Deformed chest
  • Alert baby
  • Fasciculations of tongue
  • Reduced power
  • “Two hands up” posture (often intubated)
  • Causes of hypotonia?
    • cerebral palsy
    • brain damage due to HIE
    • muscular dystrophy

Diagnosis:

  • Spinal muscular atrophy type 1 (Hoffman disease) =] - If there Peripheral hypotonia +Fasciculations of tongue?
  • Frog leg position

Infant Position:

  • Frog position
  • Hypotonia
  • Alert and simple

This is a hypotonic infant, how do you expect the power?

  • Reduced


Spina Bifida / Myelomeningocele

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Findings:

  • Sunset eye
  • Big head
  • Dilated veins in head (sign of increased ICP)

Most common cause of hydrocephalus:

  • Myelomeningocele

Next to examine:

  • Back
  • Check pulse and BP (increased ICP) Treatment:
  • Closure of myelomeningocele
  • VP shunt

sunset eye with hydrocephalus, given vp shunt


Blueberry Muffin Rash

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Associated with:

  • Hepatosplenomegaly

Main Causes:

  • CMV
  • Toxoplasmosis
  • Acute neoplastic leukemia (e.g., congenital leukemia)

Differentiation from Meningococcemia:

  • Newborn with skin rash and hepatosplenomegaly
  • Type of rash: Blueberry muffin rash
  • Not meningococcemia because there is hepatosplenomegaly


CMV Infection

img-191.jpeg|343x305img-280.jpeg|216x308img-12.jpeg|254x206 year old girl has had recurrent episodes of swelling of her hand and feet for last 6 month, these 12 episodes occur following exercise and emotional stress last for 2-3 days and resolve spontaneously. The last episode was accompanied abdominal pain, vomiting and diarrhea the results of routine laboratory workup are normal an older sister and a maternal uncle have had similar episodes as shown in photographs below

Diagnosis? CMV.

CT finding? Periventricular calcification (vs Toxo which is scattered).

Findings:

  • Microcephaly
  • Jaundice
  • Hearing loss
  • Non-blanching rash
  • Small for gestational age
  • Calcification around the ventricles (C-shape)

Memory aid:

  • C-shape calcification = CMV

Congenital Toxoplasmosis

img-8.jpegimg-219.jpeg|345x260img-415.jpeg|238x322img-416.jpeg|174x319 This child was delivered with jaundice, HSM, wide spread rashes and progressive head enlarging. Mather gave history of contact with cats early in her pregnancy.

  • Diagnosis?
    • Congenital Toxoplasmosis “Lipic Vaginal” (Lipic Vaginal), - differential - CMV (paraventricular first image - c shaped)

Findings:

  • Jaundice
  • Hepatosplenomegaly
  • Widespread rashes
  • Progressive head enlargement
  • Mother history of contact with cats early in pregnancy

Investigation? Serology (IgM and IgG).

CT Finding: Intracranial calcification (extensive cerebral calcifications) — scattered pattern.

  • CNS calcifications (tram calcification pattern)
  • Calcification in the border called “tram calcification”
  • CMV has calcification around the ventricles (C-shape)

Hypoxic Ischemic Encephalopathy (HIE)

Therapeutic Hypothermia

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Scenario: One day old baby with severe HIE - Full term newborn admitted to NICU due to severe birth asphyxia (hypoxic ischemic encephalopathy).

Q1: What is the mode of therapy?

  • Therapeutic hypothermia Head-selective (or whole body) therapeutic hypothermia (e.g., Olympic Cool Cap).)
  • Temperature: 33.5-34.5°C,
  • Duration: started within 6 hours, used for 48 hours - 2-3 days

Q2: What is the effect of this therapy?

  • Neuroprotection
  • Decrease brain injury
  • Reduce energy requirements and level of free radicals
  • Preserves anti-oxidants
  • Inhibit apoptosis
  • Reduce damage caused by 2nd stage

Indications:

  • Severe birth asphyxia

HIE Complications

A 10 days old infant, suffered a moderate severe HIE from which he recovered. He showed spastic posture, What is the abnormality seen in his face?

Facial Palsy:img-390.jpegimg-391.jpeg

Diagnosis:

  • Facial palsy (right sided)
  • LMN (Whole face affected)

Other features of HIE:

  • Fisting
  • Extension of hip
  • Flexion of knee
  • Dorsiflexion of feet

Complications of HIE:

  • Acute renal failure
  • Myocardial dysfunction
  • Coagulation impairment

Horner’s syndrome, partial ptosis Sympathetic distrubtion

  • cervical; Parasympathetic
  • thoracic; Sympathetic
  • lumbar; Sympathetic
  • sacral; Parasympathetic

6th, 7th 12th cranial palsy.


Neurofibromatosis Type 1

img-450.jpeg iris hemarto…

Pedigree:

  • Mode of inheritance: Autosomal Dominant

Clinical Findings:

  • CafĂ©-au-lait spots
  • Lisch nodules in eyes (seen via slit lamp)

Hypopigmented Area - ashleaf tuberous sclerosis

  • May indicate magnesium deficiency?? C

Nodule in Rash

Diagnosis:

  • Tuberculosis??? C

Tuberous Sclerosis -

adenoma sebacome img-449.jpeg

Findings:

  • Adenoma sebaceum
  • Shagreen patch
  • Ash leaf spots (white spots - differential includes Vitiligo)
  • Alopecia patch on head (Benqueth/Sanders syndrome)

Sturge-Weber Syndrome

Findings:

  • Port-wine stain in the face
  • Seizures
  • Tram-like intracerebral calcifications (usually same side as the stain)

Complications:

  • Seizures (focal epilepsy, usually opposite side of the brain calcifications)
  • Glaucoma


Incontinentia Pigmenti

  • Finding: A recognized neurocutaneous syndrome presenting with distinctive skin rashes along Blaschko’s lines, alopecia, and neurological symptoms.

Wilson Disease

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Slit lamp examination for diagnostics

Diagnosis? Wilson Disease.

Clinical Signs: Kayser-Fleischer ring in the cornea.

Management? D-penicillamine (copper chelation), zinc supplementation, low copper diet.



IUGR (Intrauterine Growth Restriction)

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Scenario: Infant delivered by C/S due to fetal distress at 40 weeks, birth weight 2.1 kg, severe difficult-to-control hypoglycemia.

Diagnosis:

  • IUGR

Maternal Causes:

  • Smoker
  • Poor nutrition
  • Maternal hypertension

Pathological Causes:

  • Trisomy 21
  • CMV infection
  • Congenital heart disease

Complications:

  • Hypothermia
  • Hypocalcemia
  • Hypoglycemia
  • Low Apgar score
  • Intraventricular Hemorrhage (IVH)

Long-term Complications:

  • Lower IQ
  • Cerebral palsy
  • Mental retardation


Growth Charts

Types of Failure to Thrive

Recurrent FTT (Child Abuse)

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Type:

  • Birth up to 36 months
  • Length for age and weight for age percentile

Description:

  • Both weight and length lines cross 2 centile chart twice

Diagnosis? Child abuse (recurrent failure to thrive, untreated).


Celiac Disease (FTT Pattern)

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Description:

  • Weight and length from birth to age 36 months
  • Deceleration of growth apparent at age 9 months

Diagnosis:

  • Gluten sensitivity disease (Celiac)

Next Investigation:

  • Endomysial antibodies

Congenital Abnormality Pattern

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Findings:

  • Both weight, height, and head circumference decreased
  • Due to congenital abnormality

Recurrent FTT Pattern

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Description:

  • Girl: Normal start → FTT → improved → FTT again
  • Pink chart for girls
  • Both height and weight cross 2 percentile downward twice

Diagnosis:

  • Recurrent failure to thrive

Causes:

  • Child abuse
  • Malabsorption (e.g., celiac disease)

Intermittent FTT Pattern

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Description:

  • Girl’s growth chart showing intermittent failure to thrive

IUGR Pattern

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Description:

  • Boy showing FTT, both weight and height affected
  • Eventually improved (maybe due to IUGR)


Mucopolysaccharidosis (MPS) -

Hurler Syndrome (Type 1 Mucopolysaccharidosis) Z

Metabolic storage diseases; often presents with central hypotonia. Hurler (Autosomal Recessive)

  • A rare lysosomal storage disease
  • Skeletal abnormalities, cognitive impairment, heart disease, respiratory problems, enlarged liver and spleen
  • Characteristic facies
  • Absence of alpha-L-iduronidase enzyme, responsible for degradation of MPS
  • Build up of dermatan sulfate and heparin sulfate in multiple tissues, resulting in progressive deterioration and, eventually, death

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Infant of Diabetic Mother (IDM)

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Macrosomia, Red, Polycythemia, with erbs palsy - infant of diabetic mother. persistant primitive reflect, stiff, probable for CP

mother hypoglycemic, cause permament damage to the infant - pamcreas enlargement, sequele to oversecretion insulin leading to…

  • This infant suffered of severe hypoglycemia and hypocalcemia. His mother had no antenatal care.
  • What is your diagnosis?
    • Large for GA, Infant of diabetic mother (macrosomia)

Findings:

  • Large for GA
  • Severe hypoglycemia
  • Hypocalcemia

Complications:

  • Respiratory distress
  • Polycythemia
  • Congenital malformations

Metabolic Complications:

  • Hypocalcemia (Check Calcium and Magnesium)
  • Hypoglycemia
  • Hypomagnesemia
  • Polycythemia

Congenital Malformations & Injuries:

  • ASD, VSD, TOF, TGA
  • Sacral agenesis
  • Erb’s palsy
  • Cystic hygroma


Beckwith-Wiedemann Syndrome

img-426.jpeg This baby has facial dysmorphism, macroglossia, nevus flammeus, and omphalocele. His birth weight was 4.9 kg, and he developed severe hypoglycemia soon after birth.

Findings:

  • Omphalocele
  • Macroglossia
  • Nevus flammeus
  • Birth weight 4.9 kg (macrosomia)
  • Severe hypoglycemia soon after birth

Diagnosis:

  • Beckwith-Wiedemann syndrome


Congenital Infections (TORCH)

Congenital Hypothyroidism

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Lab Findings:

  • Elevated TSH

Findings:

  • Developmental delay
  • Constipation

Complication:

  • Mental retardation

Lipoatrophy

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Scenario: 13-year-old diabetic girl for follow-up. HgA1c is 6.5, random blood glucose 260mg/dl

Finding:

  • Lipoatrophy at injection sites

Risk Factors:

  • DM
  • Hypothyroidism
  • PCOS


Hashimoto Thyroiditis

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Findings:

  • DM1 patient (Autoimmune polyendocrine syndrome)
  • Goiter

Investigations:

  • TSH, FT4, FT3
  • Thyroid antibodies (anti-TPO, anti-Tg)

Acanthosis Nigricans

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Causes/Conditions:

  • Type 2 diabetes
  • Cushing disease (and other adrenal gland issues)
  • PCOS
  • Pituitary disorders
  • Hypothyroidism
  • High doses of niacin

Investigations:

  • Fasting blood sugar
  • HgA1C

Cushing Syndrome

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Scenario: This boy presented with short stature, his hight below 3rd percentile, hid weight above 95th percentile..what is the most likely cause?

Diagnosis:

  • Cushing syndrome

Galactosemia

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Scenario: 3 month old with hepatosplenomegaly, hypoglycemia, decreased tone and muscle strength. Older brother on special milk formula.

Clinical sign? Bilateral cataracts.

Diagnosis? Galactosemia.


Leukocoria (Retinoblastoma)

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Finding:

  • White reflex in the pupil (leukocoria)
  • Cat’s eye reflex

Diagnosis:

  • Retinoblastoma


Infective Endocarditis

Signs:

  • Janeway lesions: Painless, hemorrhagic, flat plaques on palms and soles (septic emboli)
  • Osler’s nodes: Painful, reddish, raised nodules on finger pads/toes (immune complex deposits)

Cause:

  • Streptococcus viridans

Management:

  • Penicillin and gentamicin

Investigation:

  • Echocardiogram

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Herpes Zoster (Shingles)

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Scenario: 8 years old boy had severe facial pain, 2 days later skin rash appeared in the same area

Q1: What is the cause?

  • Varicella-zoster virus

Q2: What is the diagnosis?

  • Herpes zoster (shingles)

Q3: What are the clues?

  • ½ face involvement
  • Pustules
  • Secondary bacterial infection

Management:

  • Acyclovir
  • Pain killer
  • Antihistamine
  • Antibiotic (if secondary infection)

Chickenpox (Varicella)

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Type of rash: Vesiculopapular

Complications:

  • Secondary skin infections
  • Sepsis
  • Encephalitis
  • Microcephaly
  • Hydrocephaly
  • Cataracts
  • Chorioretinitis
  • Absent deep tendon reflexes
  • Horner’s syndrome
  • Hypopigmentation
  • Most common: Aseptic meningitis

Hemorrhagic Chickenpox Make sure its not immune deficiency


Shingles reactivation


Herpetic Gingivostomatitis

3 years old child presented with fever and refusal to eat, your examination showed img-122.jpeg|289x225img-374.jpeg|216x227

  • Diagnosis ?
    • Herpes simplex 1 (herpetic gingivostomatitis)

Finding:

  • Aphthous ulcers
  • Oral mucosa ulceration

Treatment:

  • Acyclovir gel
  • Severe cases: IV acyclovir

Herpes Simplex (Herpetic Labialis)

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Finding:

  • Cluster of vesicles below the lower lip (Herpetic)

Diagnosis:

  • Herpes labialis (Herpes simplex type 1)

transmission

Herpetic Whitlow

Findings:

  • HSV-1 infection on the finger (whitlow)

Management:

  • Topical acyclovir

Acute Lymphoblastic Leukemia (ALL)

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Scenario: 4-year-old boy with fever, hepatosplenomegaly

Abnormality in peripheral smear? Blast cells (lymphoblasts).

Diagnosis? Acute Lymphoblastic Leukemia (ALL).

Other Signs:

  • Anemia signs: dizziness, pallor
  • Thrombocytopenia: petechiae, purpura
  • Recurrent infections
  • Bone pain
  • Weight loss
  • Hepatosplenomegaly

Bone Marrow:

  • Single cell blast

Confirmatory Investigations:

  • Bone marrow aspiration and biopsy
  • Immunohistochemistry

Treatment:

  • Chemotherapy
  • Supportive measures

Prognosis?

  • Good prognosis if treated — children are cured in 90%
  • Males treated for 3 years, females treated for 2 years

Findings: Leukemic morphology, cant diagnosis what type - however AURE ROD findings would most likely point to AML


Pyloric Stenosis

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Scenario: weeks old male infant presented with projectile vomiting after feeding progressively worse, non bilious, no fever, no diarrhea, less active than before

Clinical Findings:

  • Signs of dehydration. Z
  • Abdominal distension
  • Visible peristalsis
  • Inverted umbilicus
  • Olive sign in epigastrium

Diagnosis:

  • Infantile hypertrophic pyloric stenosis / Congenital pyloric stenosis

Complications:

  • Hypochloremic hypokalemic metabolic alkalosis
  • Severe dehydration

Mode of Inheritance:

  • Autosomal Dominant

Management:

  • Fluid resuscitation
  • Potassium chloride and electrolyte correction
  • Surgical treatment (pyloromyotomy)


Toxicology & Emergencies

Corrosive Poisoning / Esophageal Stricture

Scenario: 3 year old poisoned at home with severe acute injury and long-term complications.

Poison type? Corrosive (bleach, disinfectants, detergents, cleaning agents).

Barium swallow finding? Esophageal stricture.

Corrosive Poisoning

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Scenario: Toddler reached chemicals area OR 15-month-old with corrosive ingestion

Findings:

  • Drooling saliva
  • Lip ulcer
  • Redness in right eye
  • NGT in place

Question: What type of poisoning?

  • Corrosive poisoning

Contraindicated Measures:

  • Induction of emesis
  • Gastric lavage
  • Administration of activated charcoal
  • Neutralizing substances with weak acid/base

Management:

  • IV Fluids and antibiotics
  • Endoscopy within 48 hours

Long-term Complication:

  • Esophageal stricture


Henoch-Schönlein Purpura / IgA Vasculitis (HSP)

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Scenario: 11-year-old female with abdominal pain, joint pain, new skin rash. Stool positive for occult blood. - 10 year old boy with purpuric skin rash and adbdominal pain what is most likely diagnosis? mention 2 complication - 8-year-old boy with joint and abdominal pain.

Rash Description:

  • Purpuric rash at buttock and extensor arms
  • Palpable purpura

Diagnosis:

  • Henoch-Schönlein purpura (HSP)
  • Part of IgA nephropathy

Complications:

  • Renal involvement (hematuria, proteinuria, chronic kidney disease, hypertension)
  • Intussusception
  • Encephalopathy
  • Massive GI bleeding
  • Acute glomerular lesion
  • In boys: scrotal edema and testicular torsion


Systemic Juvenile Rheumatoid Arthritis (Still’s Disease)

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Keywords:

  • Spiking fever
  • Rash started in the trunk
  • Growth affected (chronic condition)

Rash Type:

  • Salmon-colored rash
  • Fades with pressure

Diagnosis:

  • Systemic juvenile rheumatoid arthritis (Still’s disease)

Juvenile Rheumatoid Arthritis (JRA)

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5 years old girl who has been limping with swelling of her right knee for several months, parents note that she cannot fully extend her right knee. She does not want to walk in the morning, but seems fine later in the morning and the rest of the day. Left knee swelling is noticed for last 3 weeks.

Chronic Arthropathy Findings:

  • Knee swelling
  • Hand defects/deformities
  • Wasting of thigh muscles (indicates chronic condition)
  • No redness (indicates chronic vs acute)

Differential Diagnosis:

  • Juvenile rheumatoid arthritis (JRA)
  • SLE
  • Hemarthrosis (in hemophilia)
  • transient synovitis?septic arthritis?bruccelosis?

Scenario: 7-year-old child with limping

Abnormalities:

  • Deformity in both knees
  • Swelling in right knee
  • Muscle wasting

Causes:

  • JRA
  • Hemarthrosis due to hemophilia

Management objectives:

  • Promote normal growth and development.
  • Factor 8 (for hemophilia)
  • Aspiration and antibiotics (for septic arthritis)

if septic

If fever and red swelling knee, rule out first:

  • Septic arthritis

Organism: if septic arthritis

  • Staphylococcus


Neonatal Infection

Scenario: CBC of 2-day-old baby who looked ill, tachypneic and distressed

CBC Findings:

  • Mature neutrophilia
  • Band cells
  • Toxic granulation

Diagnosis:

  • Neonatal infection (Sepsis)

Next Investigations:

  • Blood culture
  • CRP
  • Serum lactate
  • U/E
  • Screening swab

Hemangioma

img-88.jpeg

Diagnosis:

  • Capillary (Strawberry) Hemangioma

Management:

  • Observation (often involute)
  • Propranolol
  • Systemic or intralesional steroids
  • Laser therapy


Neonatal Lupus

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Scenario: 3-month-old anti-Ro/SSA positive male infant OR 2-month-old anti-Ro/SSA positive male infant

Findings:

  • Discoid rash
  • Photosensitivity
  • Skin rash and low pH
  • Mother with facial rash occasionally pruritic

Diagnosis:

  • Neonatal SLE / Neonatal lupus / Neonatal lupus erythematosus.

Other Manifestations:

  • Malar rash (neck redness)
  • Complete heart block
  • Hepatomegaly (hepatitis)
  • Anemia
  • Thrombocytopenia (bruise)
  • Oral ulcer
  • Arthritis

Cardiac Complication:

  • Heart block

Photosensitivity

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Finding:

  • Photosensitivity of SLE (Area not covered)


Hereditary Angioedema

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Scenario: Girl with recurrent episodes of swelling of hands and feet for 6 months (12 episodes), following exercise and emotional stress, lasting 2-3 days. Last episode with abdominal pain, vomiting, diarrhea. Family history: older sister and maternal uncle with similar episodes.

Diagnosis:

  • Hereditary angioedema

Periorbital Edema

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Findings:

  • Periorbital edema secondary to fluid overload (mild cases)
  • Very severe facial edema secondary to hypoalbuminemia (severe cases)

Causes of Generalized Edema:

  • Fluid overload (mild edema): Renal failure, heart failure
  • Hypoalbuminemia (severe edema): Kwashiorkor, chronic liver disease, nephrotic syndrome, protein losing enteropathy

Causes:

  • Nephrotic syndrome
  • Liver disease
  • Heart failure
  • Anaphylactic shock
  • Angioedema


Hematology & Oncology

Hemolytic Uremic Syndrome (HUS)

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Scenario:

  • Patient with bloody diarrhea, fever, weakness, periorbital edema
  • Developed acute renal failure, microangiopathic hemolytic anemia, thrombocytopenia

Peripheral Blood Smear:

  • Abnormal shape of RBCs (fragmented RBCs/schistocytes)
  • Thrombocytopenia

Diagnosis:

  • Hemolytic-uremic syndrome

Triad:

  • Renal failure
  • Anemia
  • Thrombocytopenia

Signs:

  • Bloody diarrhea
  • Vomiting
  • Petechiae
  • Oliguria
  • Dehydration
  • Hypertension
  • Seizure

Causes:

  • E. coli O157:H7
  • Shiga toxin

Management (supportive):

  1. Hydration/Fluid replacement
  2. Managing complications of renal failure (dialysis, HTN control)
  3. Blood transfusion


Skin Lesions from Child Abuse

Sock-glove burn: & Cigarette Burns

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Pattern:

  • Sock-glove like burns
  • Multiple rounded scars (cautery marks)

Seen when:

  • Feet or hands held in water
  • Line of demarcation suggests non-accidental injury

Diagnosis:

  • Child abuse

Rib Fracture

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Finding:

  • Rib fracture
  • Healed fracture

Diagnosis:

  • Child abuse

Immersion Burns

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Scenario: 2 year old with symmetrical burns on both hands and feet, brought to ER.

Burn pattern? Thermal injuries with stocking-and-glove distribution (immersion injuries).

Accidental? FALSE — this is child abuse.


Electrical Injury

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Diagnosis:

  • Child abuse
  • Type: Neglect

Prevention:

  • Place baby in crib
  • Baby sitter

Raccoon Eyes

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Scenario: This boy presented with history of partial seizure. What will be your next step after history and examination?

Finding:

  • Periorbital ecchymosis (raccoon eyes)

Diagnosis:

  • Child abuse (basilar skull fracture)

Elbow burn (delayed presentation):


Baby Shaken Syndrome

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Scenario: 4-month girl presents to ED with recurrent vomiting, admitted, discharged stable (seen at hospital twice before), 5 days later presents with unresponsive episode, bulging fontanelles (listlessness) to PICU.

Findings:

  • Subdural hemorrhage

Diagnsois?

  • baby shaken syndrome

Complications:

  • Cerebral edema
  • Retinal hemorrhage

Scenario: 9-month-old infant with skin lesions and irritability due to native remedy

Findings:

  • Multiple cautery marks (traditional treatment)

Q1: What is the cause of lesions?

  • Due to multiple cautery marks

Q2: What are complications?

  • Infection
  • Sepsis
  • Scarring

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Physical Abuse - Cautery Marks

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Findings:

  • Multiple rounded scars (cautery marks) in abdomen and back

Management:

  • Educate the family
  • Hold the baby
  • Call the police
  • Call social workers

Child Stair Gate

img-408.jpeg

Uses:

  • Falls prevention

Car Seat

img-427.jpeg|346x304

Question: Does car seat use prevent disability?

Answer:

  • Yes, by preventing head & body injury

  • Holds the child down

  • Mandatory by law in many countries

    • Purpose: To prevent child trauma and disability.

    • Age <1 year: Seat should face opposite the driver (rear-facing).

    • Age <3 and >3: “Smle direction” chair (front vs. rear facing logic) used to prevent child trauma.

    • Stair Gate: Essential for accidental injury prevention.


diff etiology for stridor (Inspiratory)

  • Angioneurotic oedema
  • bacterial trachitis (Fever)
  • croup (Fever)
  • diphtheria (Fever)
  • epiglotitis (Fever)
  • foregin body
  • hypoglycemia

ABCDEF-----H


6 month earlier between female and male kids



Giardia lamblia Human Rota virus schistosoma mansoni - terminal schistosoma haematobium Dust mite pediculosis


Key Associations

FindingDiagnosis
C-shape calcificationCMV
Tram-track calcificationToxoplasmosis
Salmon-colored rashSystemic JRA
Blueberry muffin rashCMV/Toxoplasmosis
Target lesionErythema multiforme
Strawberry tongueKawasaki
Port-wine stainSturge-Weber
Café-au-lait spotsNF type 1
Frog position + tongue fasciculationsSMA type 1
Scissoring + fistingSpastic CP
Drooling + tripod positionEpiglottitis
Double bubbleDuodenal atresia
Boot shape heartTOF
Egg on side/stringTGA
Snowman signTAPVD
Box shape heartEbstein anomaly

Quick Reference: TORCH Infections

FeatureCMVToxoplasmosisRubellaHSV
CalcificationPeriventricular (C-shape)Tram-track (border)--
RashBlueberry muffin--Vesicular
EyeChorioretinitisChorioretinitisCataractKeratoconjunctivitis
Hearing loss+-+-

Notes on Cataracts (Leukocoria / White Reflex):

  • Associated with Galactosemia (most common metabolic), Rubella, Congenital Glaucoma, CMV, Toxoplasmosis, or can be isolated. | IUGR | + | - | + | - |


Tilt Table Test

img-306.jpeg|344x287

Technique:

  • Tilt table test
  • If drop in systolic >20, this is significant

Indications:

  • Postural hypotension
  • Diagnosis of vertigo
  • Syncope
  • Tachycardia with standing

Contraindications:

  • Coma
  • Severe anemia
  • Severe heart failure

Valsalva Maneuver

img-377.jpeg|409x285

Indications:

  • Supraventricular tachycardia
  • Decrease arterial refractory period
  • Cases of syncope

Time:

  • 5-10 seconds

Other Vagal Maneuvers:

  • Vagal stimulation via closing the nose.


Erythema Multiforme

img-87.jpeg

Scenario: Ill-looking 10-year-old boy with fever 38°C, purpuric rash widely distributed, appeared after starting antibiotic for otitis media

Q1: What is the name of skin lesion?

  • Target lesion

Q2: What is the diagnosis?

  • Erythema multiforme

differentials

  • infection
  • Herpes simplex
  • mycoplasma
  • phenoparbitol

Q3: How would you treat?

  • ICU admission
  • IV antibiotics
  • Antihistamine
  • IVIG

Complications? May develop into steven jhonson syndrome - mortality rate becomes 50%


Marginatum rheumatic fever


Erythema Marginatum

img-61.jpeg|220x433

Rash? Erythema Marginatum.

Associated condition? Acute rheumatic fever.


Scabies

img-186.jpeg|340x309

Scenario: A 9 month old infant presents with numerous excoriated, erythematous papules and pustules on the wrists, abdomen, periaxillary skin, ankles, and feet. Some of the lesions appear to be infected secondarily. The patient appears uncomfortable. Mother reports that her other children only have a few pruritic lesions. Mother denies any lesions but habitually rubs the interdigital webs of her hand

Diagnosis:

  • Scabies

Symptom Severe itching, similar family symptoms, recent hike, scabies burrows


Findings? Lymph node enlargement

Differential lymphoma until proven otherwise

infection, malignancy, congenital, …


Differentials: Phenytoin, leukemia, bad oral hygiene


Bone marrow of pediatric patient

Finding? Visceral Leishmania donovani body

Other findings huge splenomegaly, privish


Lipid storage disease, foaming


owl’s eye appearance” refers to the distinct look of Reed-Sternberg (RS) cells, which are the hallmark diagnostic feature of Hodgkin lymphoma.


Ophthalmia Neonatorum

chlamydia inclusion bodies, on periphery of cells

Differentials

  • Group B streptococcus <2wks
  • Chalmydia >2wks

treatment Erythromycin for 2 weeks 3 times day


subconjuctival hemorrhage

Sudden bleeding differentials 1- Trauma (accident, nonaccidental) 2- platelet disorder (ITP, ..) 3- Coagulation (Factors, hemoph, christm) 4- Wall (vasculitis)


Occurs with

  • Marfan syndrome
  • homosynsatornoria not synsottonosis?

Colomboma


Papilledema Increased intracranial pressure or Blood pressure


Findings Chorioretinitis,

Differentials

  • CMV
  • Congenital Toxoplasmosis

Cherry red spot


Scenario VSD, did dental, didnt get antibiotics

Findings Roth spots


Phakomata, Tuberous sclerosis


Acute otitis media


Audiometry

TypeMechanismCommon Differentials
Conductive Hearing LossProblem conducting sound waves anywhere along the route through the outer ear, tympanic membrane (eardrum), or middle ear (ossicles).- Acute Otitis Media (AOM)
- Otitis Media with Effusion (Glue ear)
- Impacted Cerumen (Earwax)
- Foreign body in canal
- Perforated tympanic membrane
- Otosclerosis
- Microtia/Atresia of the ear canal
Sensorineural Hearing Loss (SNHL)Damage to the inner ear (cochlea) or to the nerve pathways from the inner ear to the brain (Cranial Nerve VIII).- Congenital: CMV, Toxoplasmosis, Rubella (TORCH infections)
- Genetic: Usher syndrome, Waardenburg syndrome
- Acquired: Meningitis, Mumps, Ototoxic drugs (e.g., Gentamicin)
- Noise-induced trauma
- Perinatal hypoxia
Mixed Hearing LossA combination of conductive and sensorineural hearing loss (damage in both the outer/middle ear and the inner ear/nerve).- Chronic Suppurative Otitis Media (causing both ossicular damage and toxic effects on the cochlea)
- Temporal bone fractures
- Certain congenital malformations
- Otosclerosis involving the cochlea

Findings Erythema nodosum

Differentials

  • TB,
  • STEPT,
  • IBD,
  • SARCOIDISIS,
  • FUNGAL INFECTIONS
  • LEPROSY

Cutaneous leishmania (female sandfly)


Molluscum contagiosum


Slapped cheeks - parvovirus b19


Exnathema, gangrinomas - pseudomonas due bed ulcers…


Bruises 1- truama 2- platelet disorder 3- coagulation 4- vasculitis


bullae


Dystrophic Epidermolysis Bullosa













Respiratory System

Acute Epiglottitis

Scenario: 3 year old non-vaccinated boy presents with fever, worsening sore throat, and respiratory distress. Exam reveals toxic appearing child, temp 40°C, drooling of saliva, stridor and sitting in tripod position (trunk leaning forward, neck hyperextended, chin thrust forward).

Q1: What is likely diagnosis?

  • Acute epiglottitis
  • Finding: Thumb sign

Q2: How do you manage?

  • Call the Anesthesia team and prepare for Endotracheal intubation
  • First management: intubation and tracheostomy if failed
  • All patients should be monitored in ICU
  • IV Antibiotics
  • Give Rifampin for close contacts

Causes: Staph most common (Streptococcus pneumoniae + Group A strept) if vaccinated, or Haemophilus influenzae type B if not vaccinated


Croup (Laryngotracheobronchitis)

Radiographic Sign: Steeple or pencil sign of the proximal trachea

Signs:

  • Inspiratory stridor
  • Barking cough
  • Hoarseness

Causes:

  • Parainfluenza virus type 1
  • RSV
  • Influenza virus

Management:

  • Mild symptoms: Single dose of oral dexamethasone
  • Moderate to severe symptoms:
    • Supportive care: humidified air or oxygen, intravenous fluids
    • Epinephrine
    • Dexamethasone
    • Surgical intervention if patient doesn’t improve

img-331.jpeg|262x222


Pneumonia

X-Ray Finding: Consolidation

Q1: What is the diagnosis?

  • Pneumonia

Q2: What is the causative organism?

  • Streptococcus pneumoniae

Pneumothorax

Case: Tension pneumothorax, Right Side

Findings:

  1. Midline shift
  2. Lung collapse
  3. Decreased air entry

Treatment: Needle decompression


Asthma with Pneumothorax / Emphysema (CXR)

img-275.jpeg|256x387img-277.jpeg|398x380 in This PIC Be Curfiat → Check Countage of the lung Hint: Loss of contour of lung

  • Check if hyperinflated

The hint is loss of Couture of lung in the emphysema → we doubt see?

Scenario: 5 year old with 3 days of acute asthma, progressive SOB, cyanosis.

CXR findings?

  • Right-sided pneumothorax OR emphysema with left mediastinal shift
  • Loss of lung opacity
  • Other mentions in original: “Liver & mucus”, “Pneumonitis”

Management?

  • Bronchodilator, inhaled steroid
  • Suction + physiotherapy
  • If pneumothorax: chest tube — 5th intercostal space, anterior axillary line
  • Possible intubation

Cardiology

CXR Patterns

ConditionDescription
TGA (Transposition of Great Arteries)Egg on side, generalized cardiomegaly, narrow mediastinum
VSD/AVSDCardiomegaly, increased pulmonary vascular markings (plethoric lung fields)
Ebstein AnomalyMarked cardiomegaly extends wall to wall (Box Shape)
Tetralogy of FallotBoot shape heart with upward cardiac apex (RVH), concave PA segment, decreased pulmonary vascular markings
Total Anomalous Pulmonary Venous DrainageSnowman or figure of 8 - dilated vertical vein on left + brachiocephalic vein on top + SVC on right form the head; enlarged atrium forms the body
Heart FailureNonspecific cardiomegaly

Specific Images


TGA:img-193.jpeg|326x244img-200.jpeg|305x242

  • Egg on string appearance - EGG ON SIDE, generalized cardiomegaly, Narrow mediastinum Description: Knee chest position (Squating position) to treat the episodes of TOF

Snowman Sign (TAPVD):img-199.jpeg|306x240 snowman or figure of 8 Dilated vertical vein on the left and bracocephalic vein on top + superior vena cava on the right form the head of snowman, the body of snowman is formed by the enlarged atrium

Dx: Total Anomalous Pulmonary venous Drainage


Ebstein Anomaly:img-196.jpeg|327x233 Description: marked cardiomegaly extend from wall to wall (Box Shape)

Dx: Ebstein Anomaly


Tetralogy of Fallot:img-197.jpeg|284x214 Description: Boot shape heart with upward cardiac apex due to Right ventricular hypertrophy and concave pulmonary artery segment and decrease pulmonary vascular marking at peripheral lung felid.

Dx: Tetralogy of Fallot


VSD/AVSD:img-195.jpeg|282x209 Description: cardiomegaly, increase pulmonary vascular markings (plethoric lung fields)

DDx : VSD, AVSD


Cardiomegaly (Heart Failure): (nonspecific) img-194.jpeg|208x156


Heart Failure with Pulmonary Edema:img-198.jpeg|330x244

Scenario: 3-month-old with heart failure, cyanotic and cardiac murmur

Findings:

  • Small heart
  • Pulmonary edema

Surgical Scar:img-201.jpeg|0x0

  • Mid or central sternotomy scar - open heart surgeries (repair of septal defect or valve replacement)

ECG Interpretations

WPW (Wolff-Parkinson-White)

img-309.jpeg|585x115img-310.jpeg|614x319

Signs:

  • Delta wave (not always clear)
  • Short PR interval
  • Wide QRS

Complications:

  • SVT
  • Atrial fibrillation
  • Ventricular fibrillation

Management:

  • Observation (intermittent can end by itself)
  • Medication
  • Catheter ablation

Long QT Syndrome (Jervell-Nielsen-Lange)

img-312.jpeg|437x242

ECG Findings:

  • QTc >0.45 sec (more than ½ RR interval)

Can lead to:

  • Severe VT
  • Sudden death

Treatment:

  • Pacemaker with defibrillator

Causes:

  • Congenital: Primary
  • Acquired: Hypocalcemia, hypoglycemia
  • Drugs: Erythromycin, quinolones

Monomorphic VT Monomorphic ventricular tachycardia

img-314.jpeg|411x182img-123.jpeg|402x203

Finding: Regular wide QRS with v tachycardia

Treatment:

  • Stable: Amiodarone or lidocaine
  • Low BP but pulse present: Cardioversion
  • No pulse: Defibrillation

Defibrillation:

  • High energy
  • No need for sedation
  • No need for synchronization

Give 2 causes:

  • Myocardia ischemia
  • Myocarditis

How to Manage:

  • CCB
  • BB
  • Amiodarone
  • Adenosine
  • Cardioversion
  • Pulseless: defibrillation

Polymorphic VT (Torsades de Pointes)

img-325.jpeg|464x283

ECG Findings:

  • Wide QRS + ↑HR
  • Twisting around the line

Cases:

  • Myocardial ischemia
  • Hypokalemia

Management:

  • MgSOâ‚„
  • Cardioversion if in shock

Asystole

img-316.jpeg|310x141

Management:

  • Start CPR immediately (may give amiodarone)
  • No shock (only give shock in case of V.fib or tachycardia)
  • Cardiac massage

Type II Second Degree AV Block

img-317.jpeg|496x539

ECG Findings:

  • No progressive prolongation
  • Intermittent non-conducting P wave

Causes:

  • Rheumatic fever
  • SLE
  • Myocarditis
  • Electrolyte disturbance (hypokalemia, hypocalcemia)
  • CHD

Treatment:

  • Treat underlying cause
  • Pacemaker

First Degree Heart Block

ECG Findings:

  • Fixed prolongation of PR interval

Causes:

  • Rheumatic fever
  • SLE
  • Myocarditis
  • Electrolyte disturbance
  • CHD

Treatment:

  • Treat underlying cause


Third Degree AV Block

img-319.jpegimg-320.jpeg

ECG Findings:

  • Complete A/V dissociation

Causes:

  • MI in adults
  • BB, digoxin, and CCB
  • Neonatal SLE → Can cause any type of heart block Cases:
  • Maternal SLE
  • Viral myocarditis
  • Rheumatic fever
  • Coronary ischemia
  • Surgery for CHD
  • CHD

ECG Findings:

  • Bradycardia
  • Difference between atrial rate and ventricular rate
  • Atrioventricular dissociation

Treatment:

  • Pacemaker

Atrial Fibrillation

img-321.jpeg

Findings:

  • Small P waves with irregular rhythm

Management:

  • Elective cardioversion
  • Medications (Amiodarone, digoxin)

Causes:

  • Mitral stenosis
  • Hyperthyroidism
  • Cardiomyopathies
  • Myocarditis
  • Medications

Atrial Flutter

img-323.jpegimg-324.jpeg

Findings:

  • Saw-toothed appearance

Management:

  • Elective cardioversion
  • Medications (Amiodarone, digoxin)

Paroxysmal SVT

img-318.jpeg

Findings:

  • Abnormal P waves
  • Narrow QRS complex
  • Small T waves
  • ↑ HR

Management:

  • Rapid heart rate → Beta Blockers
  • If patient in shock: cardioversion
  • If patient unstable: medications like adenosine, amiodarone
  • If patient stable: carotid massage, valsalva maneuver, ice bags, cold shower

Ventricular Fibrillation

img-455.jpeg

Treatment:

  • ER:
    • Still has pulse → Cardioversion
    • No pulse → Defibrillation
  • ICU:
    • Amiodarone → IV Line
  • ICU for any resone - Amidaron → IV Line in ICU PIR

Kawasaki Disease

Physical Findings:

  • Strawberry tongue
  • Bilateral conjunctival injection
  • Mucosal changes
  • Cervical lymphadenopathy

Complication:

  • Coronary artery aneurysm

Differentiation from Hand-Foot-Mouth Disease:

  • No strawberry tongue in HFMD
  • Fever >5 days in Kawasaki vs 2 days in HFMD

img-50.jpeg|216x307img-51.jpeg|198x280img-52.jpeg|182x259img-53.jpeg|216x217img-54.jpeg|195x194img-55.jpeg|189x190img-187.jpeg|228x230img-188.jpeg|278x226img-189.jpeg|294x185img-190.jpeg|302x209


VSD Case

Scenario: At 2-week checkup, a murmur is heard for the first time in an acyanotic well baby. Diagnosis of VSD with left-to-right shunt is made.

Q1: Is the family justified for being upset about not hearing murmur in newborn period?

  • In newborn there is decreased pulmonary vascular resistance (no murmur), but after 4-6 weeks will increase and cause murmur

Q2: Is it possible that CHF will develop before next visit at 1 month?

  • Yes, if it is large VSD

Q3: Is pulmonary hypertension likely to be present at this time?

  • No

Kernicterus

img-386.jpeg

Scenario: 5-day old full-term infant develops severe hyperbilirubinemia. Despite phototherapy and exchange transfusion, condition deteriorates.

Signs:

  • Arching of back
  • Extension of neck
  • Increased tone of upper limb
  • Opisthotonus Z
  • Fisting

Diagnosis:

  • Kernicterus

Causes:

  • Hemolytic disease of the newborn
  • Sepsis with DIC
  • Prematurity

Complications:

  • CP
  • Encephalopathy
  • Mental retardation
  • Delayed milestones

Abdominal Wall Defects

Gastroschisis

img-217.jpeg

Characteristics:

  • Usually no long-term sequelae
  • Treatment: Surgical repair

Omphalocele

img-218.jpeg

Characteristics:

  • Usually associated with other anomalies
  • Treatment: Surgical repair

Multi-organ Failure

img-424.jpeg

Scenario: 7-day-old infant C/S delivery due to severe fetal bradycardia. Delivered completely limp, offered prolonged resuscitation. Currently comatose, anuric, very high liver enzymes.

Diagnosis:

  • Multi-organ failure because of birth asphyxia

Clues:

  • C/S
  • Bradycardia

Roseola Infantum

img-183.jpeg|267x201

Scenario: Infant with high fever (39.4-40.6°C) lasting 2 days. After fever ended, rosy-pink rash appeared mostly on trunk, neck, and arms. Rash not itchy, lasted 2 days.

Diagnosis:

  • Roseola infantum

Hand-Foot-Mouth Disease

img-431.jpeg|273x309img-432.jpeg|315x317img-433.jpeg|241x192img-434.jpeg|90x186

Scenario: A 2 years old child presented with two days history of fever, malaise, abdominal pain. Mother brought him to medical attention today because of the appearance of this rash.

Diagnosis:

  • Hand-foot-mouth disease

Cause:

  • Coxsackievirus A16

Why not Kawasaki:

  • No strawberry tongue
  • Fever only 2 days (Kawasaki >5 days)

Mongolian Spot

img-177.jpeg|399x322

Finding:

  • Blue-black spot on buttocks

Diagnosis:

  • Mongolian spot

Management:

  • Assure the mother (benign)

Gum Hyperplasia

img-213.jpeg

Causes:

  • Poor oral hygiene
  • Medications (cyclosporine, phenytoin)

Hirsutism

img-214.jpeg|357x203

Causes:

  • Cyclosporine
  • Minoxidil (antihypertensive)

Bitot Spot (Vitamin A Deficiency)

img-237.jpeg|345x228

Finding:

  • Silvery and scaly area in the sclera
  • Bitot spot

Cause:

  • Vitamin A deficiency

Encholi’s Pigment

img-411.jpeg|278x370


Gastroenterology


Duodenal Atresia

img-179.jpeg|257x251img-236.jpeg|261x248

X-Ray Finding:

  • Double bubble sign (should not see gas beyond the double bubbles)
  • 1 bubble in stomach, 1 in 1st part of duodenum

Associated with:

  • Down syndrome

Management:

  • Duodenostomy

Hirschsprung Disease

img-125.jpeg|289x265img-334.jpeg|285x276describe x-ray There is fecal impaction, transitional zone (dilated part proximally and constricted part distally)

Barium Enema Findings:

  • Fecal impaction
  • Transitional zone (dilated part proximally, constricted part distally)
  • Narrow distal segment
  • Dilated proximal segment
  • Funnel-shaped dilatation at level of transitional zone

Causes:

  • Absence of ganglion cells (aganglionic megacolon)

Presentations:

  • Delayed passage of meconium
  • Chronic constipation
  • Toxic megacolon
  • Signs of intestinal obstruction

Confirmation:

  • Rectal biopsy

Management:

  1. Resuscitation, NPO and IV fluids
  2. Antibiotics
  3. Rectal tube, irrigation
  4. At age 6-12 months: resection of aganglionic segment and anastomosing (formal pull-through procedure)

Intussusception

img-226.jpeg|388x308img-336.jpeg|292x460img-337.jpeg|255x454

  • 18 Months old boy presented with crying and vomiting.
  • A bloody stool was passed on the day of the imaging examinations.

Diagnosis? Ileocolic intussusception.

Investigation? Barium enema.

Sign?

  • Cut-off sign in the middle
  • Coiled spring appearance / spring sign

Etiology:

  • Idiopathic
  • Secondary to: HSP, intestinal polyps

Emergency:

  • Type of obstruction

Treatment:

  1. NPO/IV fluids
  2. NGT aspiration
  3. IV antibiotics
  4. Hydrostatic reduction with Barium/air enema
  5. Laparotomy and resection if needed

Complications:

  • Ischemia and necrosis

Necrotizing Colitis

img-216.jpeg|270x180

History:

  • Presented with renal failure, anemia, low platelets

DDx:

  • SLE
  • Hemolytic uremic syndrome

Chronic Constipation


Nephrology & Urology

Vesicoureteral Reflux (VUR)

img-98.jpeg|328x431

History:

  • Recurrent UTIs

Modality:

  • MCUG (micturating cystourethrogram)

Findings:

  • Posterior urethral valve
  • Dilated ureters
  • Tortuous ureters
  • Dilated ureteric pelvis bilaterally (hydronephrosis)

Diagnosis & Grading

  • Studies: Renal US (Typically first); MCUG (to confirm diagnosis); RNC (for follow-up).

International Grading System (MCUG Findings):

GradeDescription / Findings
Grade IInto a nondilated ureter only.
Grade IIInto the pelvis and calyces without dilation.
Grade IIIMild to moderate dilation of ureter, pelvis, and calyces; minimal blunting of fornices (become close).
Grade IVModerate ureteral tortuosity and dilation of pelvis and calyces (adhered to each other).
Grade VGross dilation; significant tortuosity; loss of papillary impressions; blunting of calyces.

img-31.jpegimg-32.jpeg

Risk Factors:

  • Congenital
  • Holding voiding
  • Chronic constipation
  • Recurrent UTI

Complications:

  • Renal scarring
  • Hypertension
  • End-stage renal failure

Management:

  • Antibiotic prophylaxis
  • Surgery for grades 4-5

img-230.jpeg


Posterior Urethral Valve (PUV)

img-293.jpeg|304x319

Modality:

  • MCUG / VCUG (voiding cystourethrogram) only in boys

Findings:

  • Dilated proximal urethra
  • Dilated ureter
  • Dilated bladder
  • Dilated posterior urethra

Only in boys

Can be diagnosed antenatal and prevented!

Complications:

  • Renal failure
  • UTI

Treatment:

  • Surgical removal of the valve
  • Catheter or drain procedure as temporary measure

Prune Belly Syndrome

img-207.jpeg|298x276img-208.jpeg|347x272

Triad:

  • Hydronephrosis
  • Undescended testis
  • Deficient abdominal musculature

Characteristics:

  • Rare syndrome
  • Sporadic, not inherited
  • Exclusively occurs in boys

Bladder Exstrophy (Ectopia Vesicae)

img-209.jpeg|259x272

Characteristics:

  • Congenital anomaly with bladder outside abdomen
  • Treatment: surgical
  • Can lead to bladder dysfunction

Renal Stones

img-235.jpeg|377x279

Best Investigation:

  • Unenhanced spiral CT (most sensitive)

Bilateral Nephrocalcinosis

img-234.jpeg|382x251

Plain X-ray:

  • Bilateral nephrocalcinosis

Causes:

  • Hypercalcemia → hypercalciuria
  • Hyperparathyroidism
  • Isolated hypercalciuria
  • Bartter kidney disease
  • Distal renal tubular acidosis

Renal Artery Stenosis

img-238.jpeg

After angioplasty:

  • Improvement in renal artery stenosis

Horseshoe Kidney

Characteristics:

  • Make sure no other conditions
  • More prone to trauma
  • More liable for obstruction

Bilateral Renal Agenesis

img-227.jpeg

Findings:

  • Squashed face (oligohydramnios)

Prognosis:

  • Not compatible with life
  • Die usually due to pulmonary hypoplasia

Hypospadia

Findings:

  • Abnormal opening in the urethra (ventral aspect)

Important:

  • Circumcision is contraindicated because the foreskin will be used later to close the opening
  • Surgical repair needed later

Chordee

Findings:

  • Flexion deformity of the penis
  • Due to contraction secondary to delayed hypospadia repair

Cast Types

img-232.jpeg|349x184img-233.jpeg|344x194

TypeDescriptionIndication
RBC CastWell demarcatedGlomerular disease
Granular CastDenatured RBCsRenal tubular damage

ITP (Immune Thrombocytopenic Purpura)

img-176.jpeg

Q1: What is the only investigation that will help you?

  • Platelet count

Q2: What is the serious complication?

  • Intracranial hemorrhage

Iron Deficiency Anemia

img-175.jpeg|358x235

Peripheral Blood Smear:

  • Microcytic hypochromic RBCs

Q1: What is the possible cause?

  • Iron deficiency

Q2: What is the treatment?

  • Iron supplement


Perthes Disease

img-287.jpeg|593x579

Diagnosis:

  • Perthes disease (Legg-CalvĂ©-Perthes disease)

Cause:

  • Avascular necrosis of the femoral head

Most Common Cause of Limping in Children:

  • Transient synovitis

Risk Factors:

  • Sickle cell disease

Down Syndrome (Trisomy 21)

img-56.jpeg|211x231img-57.jpeg|247x230

Eight-year-old boy with dysmorphic features and learning disability. She was operated for congenital heart disease at infancy.

Diagnosis? Down Syndrome.

Most common cause? Trisomy 21 (meiotic non-disjunction).

Which investigation helps in assessing this patient?

  • Thyroid hormone levels

Describe facial features? Epicanthic fold, brush field spots in iris, strabismus, upslanted palpebral fissures

What is the most common Musculoskeletal Problems? Atlantoaxial instability

What are the long-term complications associated with Down Syndrome? Leukemia, hypothyroidism, and obesity.


Marfan Syndrome / Ehlers-Danlos Syndrome

img-220.jpeg|402x231

Findings:

  • Hypermobility of joints (hyperelasticity)
  • Long fingers

Diaphragmatic Hernia

img-228.jpeg|306x370img-229.jpeg|343x434

  • Anterior diaphragmatic hernia

Meckel-Gruber Syndrome

Associated with:

  • Occipital encephalocele

Occipital Encephalocele

img-215.jpeg

Findings:

  • Opening in skull → herniation of brain tissue

Important:

  • Any midline swelling from base of nose to base of neck → Don’t send for surgical excision (might be encephalocele)
  • Do CT scan to ensure no brain tissue

Part of:

  • Meckel-Gruber syndrome

This patient presented with hypocalcemia

Most likely diagnosis? X Pseudohypoparathyrodism


Infectious Diseases

Bacterial Infections

Group B Streptococcus (GBS)

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  • Baby with severe resp distress after birth. Blood cluture shows gram +ve cocci
  • Cause ?
    • GBS
  • 2nd picture shows ?
    • Gram negative N.meningitides

Meningococcemia

,Parents bring their child in for evaluation due to acute development of high fever, malaise and lethargy. On exam, the patient is mottled with poor perfusion, tachycardic, and has developed a new rash img-185.jpeg!

Findings:

  • Purpura, petechiae, ecchymosis (non-blanching)
  • Mottled appearance
  • Poor perfusion
  • Tachycardia

Blood Culture:

  • Gram negative N. meningitidis

Diagnosis:

  • Meningococcemia

Scenario: Baby with severe respiratory distress after birth

Blood Culture:

  • Gram positive cocci

Cause:

  • GBS


Tuberculin Skin Test

Route of injection:

  • Intradermal

When positive:

  • When there is 5mm induration in endemic area

Procedures & Devices

Intraosseous Infusion

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Indications:

  • Administration of fluids and medications
  • Unacceptable IV line
  • Patient in shock needing rapid access

Contraindications/Precautions:

  • Infection at entry site (cellulitis)
  • Osteogenesis imperfecta
  • Fracture
  • Severe bleeding

Procedure:

  • After 2nd trial, change site

Peak Expiratory Flow Meter

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  • end Exisiotomy meter What it measures:
  • FEV1 (Forced Expiratory Volume in 1 second)

Automated External Defibrillator (AED)

Uses:

  • Cardioversion
  • Defibrillation
  • Pacing for ↓ HR

Indications:

  • Pulseless ventricular tachycardia (VT)
  • Ventricular fibrillation (VF)
  • Cardiac arrest due to or resulting in VF

Contraindications:

  • Dysrhythmias
  • Multifocal atrial tachycardia

Error:

  • Not making paddles closer (may shock self)

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Peak Expiratory Flow Meter

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  • end Exisiotomy meter What it measures:
  • FEV1 (Forced Expiratory Volume in 1 second)

Spirometry / Peak Expiratory Flow Meter

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Device? Spirometry / Peak expiratory flow meter

What does it measure? PEF (Peak Expiratory Flow) / FEV1.


Aerochamber Spacer with Mask

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Name:

  • Aerochamber spacer with mask, flow valve and MDI

Age:

  • With mask: 2-3 years
  • With mouthpiece: 6-9 years

Indication:

  • Bronchial asthma below 5 years

Advantages:

  • Slows down medicine delivered from metered-dose inhaler
  • Medicine stays in spacer for child to breathe into lungs
  • Without spacer, medicine sprays directly into mouth/throat, less reaches lungs

Medications used:

  • Bronchodilator
  • Corticosteroid

Positive Pressure Ventilation (PPV)

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Procedure:

  • PPV by Ambu bag

IV Catheter Insertion

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Type of insertion: Intravenous line placement