Trematodes

Drugs Active Against Trematodes

• Praziquantel; permeability to calcium → paralysis → vacuolization & death
• Metrifonate,
• Oxamniquine
• BithionolY

Medically important trematodes are:

1. schistosoma species (blood fluke)
2. clonorchis sinesis (liver flukes in southeast Asia)
3. paragonimus westermani ( lung fluke in Asia,India)