Fenoldopam

Mechanism:

 It stimulates D1 receptors in peripheral arteries leading to VD and diuresis.  

Uses:

  • it is given by continuous i.v. infusion
  • Treatment of hypertensive emergencies.
  • Treatment of post-operative hypertension.  

Side effects:

  • Hypotension and reflex tachycardia
  • Increase IOP so it should be avoided in patients with glaucoma.