Therapeutic uses:

  • Severe systemic hypertension.
  • Hypertension in pregnancy (2nd choice after α-methyldopa).  

Side effects:

  • Hypotension and reflex tachycardia.
  • Salt and water retention.
  • Headache, Anginal pain, Nausea, Dizziness (HAND).
  • Systemic lupus erythematosis (SLE)-like syndrome in slow acetylators. (same as isoniziad [sp])