Rifampin (rifampicin), rifabutin, rifapentine,
rifaximin (not used for mycobacterial disease) The rifamycins are potent inducers of the cytochromeP450 system, and patients receiving them should always be screened for drug interactions. In addition to their activity against mycobacteria, rifamycins are active against many “typical” bacteria as well and are sometimes added to other therapies, particularly to treat difficult methicillin-resistant Staphylococcus aureus (MRSA) infections