• It is prepheral symmetrical polyneuropathy .
  • Motor nerve affection can lead to Ptosis,foot drop.
  • Sensory nerves affection more common than motor nerves .

sensory nerve affection of feet and hand called ’’Glove and Stocking’’ with the following manifestations:

  1. numbness and paresthesia(altered sensation),burning,tingling
  2. loss of pain sensation ⇒ unnoticed injury.

Complications :

  1. ulceration (painless) with diffcult healing due to diffuse vascular injury.

  2. charcot neuroarthropathy: damage of weight bearing joints as knee and ankle joints also damage of tarsal and metatarsal joints in foot.

  3. Callosities: hardening and thickning of skin specially in pressure areas with prolonged friction.

Diabetic foot Pathogenesis

  1. decrease sensitivity ⇒ unnoticed injury ⇒ infection.

  2. autonomic dysfunction of sweat glands ⇒ skin fissure, cracks, callus.

  3. motor nerve dysfunction ⇒ high arched foot and susceptibility to injury.

Diabetic foot care