• It is prepheral symmetrical polyneuropathy .
  • Motor nerve affection can lead to Ptosis,foot drop.
  • Sensory nerves affection more common than motor nerves .

sensory nerve affection of feet and hand called ’’Glove and Stocking’’ with the following manifestations:

  1. numbness and paresthesia(altered sensation),burning,tingling
  2. loss of pain sensation unnoticed injury.

Complications :

  1. ulceration (painless) with diffcult healing due to diffuse vascular injury.

  2. charcot neuroarthropathy: damage of weight bearing joints as knee and ankle joints also damage of tarsal and metatarsal joints in foot.

  3. Callosities: hardening and thickning of skin specially in pressure areas with prolonged friction.

Diabetic foot Pathogenesis

  1. decrease sensitivity unnoticed injury infection.

  2. autonomic dysfunction of sweat glands skin fissure, cracks, callus.

  3. motor nerve dysfunction high arched foot and susceptibility to injury.

Diabetic foot care