Magnesium hydroxide:(Milk of magnesia)
- Non-absorbable antacid has rapid onset of neutralization increasing pH up to 8-9.
Magnesium oxide and magnesium trisilicate:
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neutralize acid slowly and have slow onset of action, and long duration. Magnesium trisilicate also coats base of ulcer by Sico2 (Physical action).
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*They increase gut motility and produce diarrhea.