Nicotine replacement therapy (NRT)

Nicotine Replacement Therapy (NRT)

Table 10.2 Pharmacological therapy for Nicotine addiction

• Nicotine replacement therapy (NRT)

  • Transdermal nicotine patch (Long-acting)
  • Nicotine lozenge (Short-acting)
  • Nicotine gum (Short-acting)
  • Nicotine nasal spray (Short-acting)
  • Nicotine inhaler (Short-acting)

• Non-nicotine replacement therapy (Non NRT)

  • Varenicline
  • Bupropion

Medication

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• Patch

  • precautions / CI
    • – Pregnancy – Immediately after MI (within 2 weeks) – Arrhythmia – Unstable Angina Pectoris
  • SE
    • – Localized skin reaction/irritation
    • – Sleep disturbance
    • – Headache
    • – Nausea
    • – Dizziness

• Lozenge

  • SE
    • – Mouth Irritation or ulcers
    • – Hiccup
    • – Nicotine dose-related symptoms;

• Nicotine gum

  • SE
    • – Gastric Irritation
    • – Jaw pain
    • – Hiccup
    • – Excess salivation
    • – Abdominal pain, nausea, vomiting, headache, and palpitations

• Nasal spray

  • precautions / CI
    • – Severe reactive airway disease
  • SE
    • – Throat irritation
    • – Rhinitis
    • – Sneezing
    • – Tearing

• Inhaler

  • SE
    • – Mouth and throat irritation
    • – Bronchospasm