Retinitis Pigmentosa
Pigmentery dystrophy
- Chronic, progressive, inherited disease
- Cone cell, rod cell and RPE dystrophy
- Inheritance pattern: AD, AR, X-link
- Onset age: childhood
- Bilateral eyes involved
Clinical Manifestation
- Nyctalopia is the first symptom “Nightblindness”
- Fundus:
- Optic disc “wax” color, “bone spicule” pigment deposition
- Constriction of visual field
- FFA:
- Window defect, blocked fluorescein in pigment deposition at early stage, hypofluorescence and the fluorescein of choroid is seen at late stage
Fundus - three findings
- Optic disc wax color,
- Bone spicule pigment deposition
- Attenuation or narrowing blood vessels
Treatment
- Genetic counseling
- Avoiding sunlight and UV
- Vasodilator, Vitamins
- Supplement of taurine
- Low vision aidsZ
- Grid laser coagulation is used with caution for CME
Stemm cell retineR