Ketoconazole

Clinical Uses

• Systemic and mucocutaneous infections.
• Prevention of Candida infection in immune suppressed patients. •

Adverse Reactions

• Mild side effects: GI distress and pruritus –
• Serious side effects:
  1. Hepatic toxicity - The drug must be discontinued if hepatitis occurs. •
  2. Gynecomastia - inhibition of testosterone synthesis and adrenocortical steroid Ketoconazole