Mechanism of action
facilitates GABA mediated neurotransmission in nematodes causing immobilization of the parasite, facilitating its removal by reticuloendothelial system.
Uses
Drug of choice in treatment of onchocercosis, and threadworm infection
Side Effects
Mazzotti reactions; occular damage (due to killing of microfilaria) and includes,fever, joint pain, rash hypotension,tachycardia