Predisposing factors:

Manifestations:

Cardiac:

  • Bradycardia and variable degree of heart block.
  • Paroxysmal atrial tachycardia
  • Any type of arrhythmia (e.g. ventricular premature beats, bigemeny, trigemeny, ventricular tachycardia, etc.)

Extracardiac:

  • GIT: anorexia, nausea and vomiting (due to ++ of CTZ).
  • CNS: headache, delirium, hallucination, and convulsions.
  • Vision: yellow vision , diplopia, etc. due to retrobulbar neuritis.
  • Others: skin rash, gynecomastia, galactorrhea.