Spectrum Very broad spectrum
Drugs: Carbencillin, Ticarcillin, Azlocillin, Mezlocillin, and Piperacillin They are broad-spectrum, but should only be used for pseudomonas, ampicillin resistant proteus, and anerobes. (eg. Bacteroids fragilis causing intrabdominal sepsis)
Cons: Beta Lactamase susceptible (can be combined with clavulanic acid)
Pros: Have an amazing synergetic effect when combined with Aminoglycosides