Amikacin and Netilmicin : Less potent than gentamicin (2-4 times less potent), but has broader spectrum than other aminoglycosides. Resistant to inactivating enzymes so it is used for gentamicin resistant cases.
- Potency than Gentamicin but Broader spectrum (Synthetic)
- Resistant for Inactivating enzyme so can be used for Gentamicin resistant cases.