Closed loop method:

  • It can measure blood glucose level by automatic glucose sensor and according to it, it releases insulin.
  • Used mainly in acute cases e.g. ketoacidosis, before surgery.

Open loop method:

  • This type can’t measure blood glucose level (has no sensor).
  • It releases insulin according to a calculated rate.
  • Used mainly in chronic administration.

Complications of artificial pancreas:

  • Hypoglycemia (excess insulin delivery)
  • Ketosis (pump failure)
  • Infection (locally).