Simple goitre

Aetiology:

• Endemic (iodine deficiency), goitrogenous food (cabbage), enzymatic deficiency of hormone synthesis

• Gland enlarges, follicle filled with colloid, multiple nodule filled with colloid & cyst formation
• Neck Swelling- no symptom multiple/solitary nodule dyspnoea, dysphagia

Investigations:

• Normal hormones, U/S, CT

Treatment:

• L-thyroxine suppression therapy – 0.1-0.2 mg/day, Rarely effective
• Surgery: Compression, cosmetic, ? Malignancy
• Total thyroidectomy