Drugs for subcutaneous and systemic mycotic infections including Opportunistic mycoses:
- Polyene antifungal (Amphotericin B) Highly toxic drug - systemic and mucocutaneus lish
- Antimetabolite antifungals (Flucytosine) meningitis treatment combination w/ 1#
- Azole antifungals (Imidazoles and triazoles);
- Echinocandins (Caspofungin, micafungin, and anidulafungin)
Examples of Organisms
- Cryptococcosis - cryptococcus neoformans
- Candidiasis - C. albicans
- Aspergillosis - Aspergillus fumigatus A. niger, A. flavus
Opportunistic mycoses
Group of mycoses caused by saprophytic fungi in immuno- compromised individuals
Examples of immunocompromised people
- HIV infected patients.
- Pregnant women.
- Transplant persons.
- Patients receiving chemotherapy or radiotherapy.
- Certain cancers and genetic disorders.