Medical conditions in pregnancy

ConditionMaternal risksFetal/neonatal risksAntenatal managementIntrapartumPostpartum/NeonatalUse/avoid meds (key)
Diabetes (pre‑existing & GDM)Hypo/Hyperglycemia, DKA, infections, preeclampsia, CSMiscarriage (pre‑DM), anomalies (pre‑DM), macrosomia, shoulder dystocia, polyhydramnios, IUGR (vascular), IUFD, neonatal hypoglycemia, RDSPreconception HbA1c, folate 5 mg; stop ACEi/ARB/statin; tight glycemic control (fasting ~70–95 mg/dL; 1‑h PP <140); diet + exercise; metformin/insulin as needed; aspirin 150 mg nightly from 12 w if risk; anatomy scan + serial growth scans; fetal echo if HbA1c highMaintain glucose 70–110; IV insulin/dextrose protocol if on insulin; continuous CTG if indicated; avoid prolonged labour if EFW >4.5 kg (discuss mode)GDM: stop agents after delivery; test at 6–12 w with OGTT; long‑term T2DM prevention; neonatal glucose monitoringUse: insulin, metformin (selected). Avoid: ACEi/ARB, statins.
Hypertension (chronic, gestational, preeclampsia)Severe HTN, stroke, renal/liver injury, HELLP, eclampsia, abruption, pulmonary edemaIUGR, oligohydramnios, prematurity (iatrogenic), IUFDTarget BP ≈135/85; meds: labetalol 1st line, nifedipine, methyldopa; aspirin 150 mg from 12 w to 36 w; baseline labs (CBC, LFT, creatinine, urine P/C); serial growth + Doppler; preeclampsia surveillanceMgSO4 for severe features/eclampsia; fluid restriction; continuous CTG; avoid ergometrine; aim VD unless obstetric indicationMonitor BP 72 h–2 w; adjust meds; counsel CVD risk; neonatal: observe if late‑pretermUse: labetalol, nifedipine, methyldopa; Avoid: ACEi/ARB, NSAIDs in severe HTN/preeclampsia (PP), ergometrine.
AsthmaExacerbations, hospitalization, ↑ mortality (if uncontrolled), preeclampsiaLBW, preterm, neonatal asphyxiaAvoid triggers; step‑wise therapy: SABA (salbutamol), ICS; add oral steroids for exacerbations; O2; antibiotics if infection; most worsen in 3rd tri; monitor controlO2, bronchodilators, steroids; avoid prostaglandins for induction that exacerbate asthma; VD unless CS indicated; continuous CTG if severeUsual inhalers safe in lactationUse: salbutamol, ICS, oral steroids if needed. Avoid: carboprost (PGF2α); use caution with labetalol in severe asthma.
Thyrotoxicosis (Graves’ common)HTN, preeclampsia, heart failure, thyroid stormMiscarriage, IUGR, preterm, IUFD, fetal hypo‑/hyperthyroidism (TSI/drugs)TFTs each trimester; PTU preferred (less teratogenic); serial US for growth/goiter; manage symptoms; plan cord blood TFTClose monitoring in labour; continuous CTG; aim VDCord TFT; adjust maternal dose; watch neonatal thyroid dysfunctionUse: PTU (early), consider switch to methimazole after 1st tri; Avoid: overtreatment causing fetal hypothyroidism.
Sickle cell diseasePain crises, infections, ACS, VTE, cardiomyopathy (iron overload), strokeMiscarriage, IUGR, prematurity, stillbirthMDT care; partner screening; folate 5 mg, penicillin if hyposplenic; stop iron chelators; screen urine for infection each visit; crisis: analgesia, O2, IV fluids, antibiotics if infection; serial growth/Doppler; thromboprophylaxis; consider prophylactic antibioticsAim VD; avoid hypoxia/dehydration; continuous fetal monitoringThromboprophylaxis; infection vigilanceUse: folate, penicillin, LMWH if indicated. Avoid: hypoxia, dehydration; chelators during pregnancy.
Iron deficiency anemiaFatigue, infections, transfusion risk, decompensation with PPHFetal hypoxia, abnormal FHR, fetal death if severe (Hb <6)Screen CBC (booking, 24–28 w); ferritin <30 µg/L confirms IDA; diet + oral iron (ferrous sulfate 1st line; adjust for tolerance); IV iron if severe/intolerant; transfuse if Hb <6 g/dL with compromiseOptimize Hb before delivery; plan hemorrhage precautionsContinue iron 3 mo and at least 6 w PP; monitorUse: ferrous salts; IV iron when needed. Avoid: tea/coffee with iron; unnecessary transfusion.
UTI (ASB, cystitis, pyelonephritis)Pyelonephritis, sepsis, anemiaPreterm labour, LBWDipstick + confirm MSU; treat all bacteriuria: 3–7 d; cystitis: 7 d; pyelo: 10–14 d; choose pregnancy‑safe antibiotics; test of cureTreat aggressively if pyelo; fluids; consider admissionRe‑screen if recurrentUse: appropriate abx per local sensitivity (e.g., cephalexin, amoxicillin‑clavulanate, nitrofurantoin except near term).
EpilepsySeizures, trauma, SUDEP (rare), ↑ hypertensive d/o, hemorrhage, pretermCongenital malformations (AED‑related), neurodevelopmental effects (valproate), fetal hypoxia if maternal seizuresPre‑pregnancy: folate 5 mg; avoid valproate, minimize polytherapy, lowest effective AED dose; obst‑neuro co‑care; anomaly scan 18–20 w; growth scans if on AEDsContinue AEDs; seizure treat with benzodiazepines; safe analgesia: epidural, Entonox; avoid pethidine; CS only for obstetric/poor control; continuous CTG if seizuresSeizure risk ↑ first 72 h; adjust AED dose to avoid toxicity; breastfeeding encouraged; screen for PPDUse: levetiracetam, lamotrigine (common choices). Avoid: valproate; avoid pethidine.
Cardiac disease (general principles)Decompensation, arrhythmia, HF, thromboembolismIUGR, FGR, prematurity (iatrogenic), fetal hypoxiaMDT obst‑cardiology; baseline + 28 w echo; anticoagulate if PH, prosthetic valves, AF (LMWH preferred esp. 1st/3rd tri); monitor for fluid overload; treat triggers (anemia, infection); plan labourAvoid supine; careful fluids; epidural beneficial; keep 2nd stage short (assisted delivery if needed); avoid induction if possible; antibiotics if structural defect; active 3rd stage with oxytocin (give slowly); avoid ergometrineHigh‑level monitoring until hemodynamics stabilize; judicious oxytocin; VTE prophylaxisUse: LMWH; carefully titrated oxytocin. Avoid: ergometrine; excessive fluids.

Quick notes for viva

  • Mode of delivery: Most conditions → vaginal delivery unless obstetric indication for CS. Keep second stage short for significant cardiac disease.
  • Thromboprophylaxis: Consider in SCD, high‑risk cardiac disease, and other VTE risks.
  • Continuous fetal monitoring: When maternal status unstable (e.g., severe asthma, thyrotoxicosis in labour, seizures).
  • Drugs to remember to avoid: ACEi/ARB (pregnancy), valproate (pregnancy), ergometrine (HTN/cardiac), carboprost in asthma, pethidine in epilepsy, iron chelators in pregnancy.

Instruments

InstrumentMain uses/indicationsContraindicationsKey complications/notesImage
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Obstetric forceps (Wrigley’s, Simpson’s, Kielland’s, Piper)Maternal: cardiac disease, toxaemia, weakness, maternal distress. Fetal: cord prolapse, malpositions (OP, DTA, face), after-coming head, fetal distress. Prolonged 2nd stage. Aid delivery/pick head in C-section.Hx of cephalopelvic disproportionMaternal trauma, sepsis, shock, pelvic joint injuries, PPH, fistula/incontinence. Fetal: soft tissue compression, cranial injury. Prereq: fully dilated, engaged head, adequate pelvis/anaesthesia, empty bladder/rectum, episiotomy, experienced operator
Vacuum extractor (ventouse: metal/plastic)Same as forceps except face/after-coming head. Can help deliver head out of lower-segment C/S.Face, breech, after-coming head; GA <34 w; prematurity; mod/severe CPD; fetal/maternal distress needing immediate delivery; after 3 failed pulls → C/SFetal scalp/skull injuries (cephalohematoma, ICH, lacerations, necrosis, alopecia); vaginal/cervical injury; ↑ risk cervical incompetence. Prereq: fully dilated, engaged head, GA >34 w, adequate pelvis, experienced operator
Sponge holding forcepsHold sponges/swabs; scrub abdomen pre-op
Backhaus towel clampSecure drapes/towels; grasp tissue; hold/reduce small bone fracturesPerforating clamp
Scalpel handlesSkin incisions in C-section
Artery forcepsHemostasis; retract tissue/skin; hold stay sutures; hold tissue/skin
Allis forcepsHold tough tissue (rectus sheath), fascia; grasp soft tissues (breast/bowel)Atraumatic for prolonged hold
Doyen’s retractorRetract bladder during C-section; protect during uterine suturingIf misapplied → bladder contusion
Green Armytage forcepsControl bleeding from uterine edges; assist suturing in C-section
Mayo scissors (curved)Cut thick tissues (uterus, muscle)
Langenbeck retractorsRetract skin during closure at CS/laparotomy
Needle holdersHold/lock needles for suturing
Cusco’s (duck’s) speculumExpose cervix/vaginal walls; swabs; apply instruments; IUD; HSG; biopsiesPros: easy, self-retaining, adjustable. Cons: hides walls unless withdrawn; limited wall protection in cautery
Sim’s vaginal speculumExpose anterior vaginal wall; drainage via groove; operative spaceNeeds assistant; difficult with cystocele
Tenaculum/Vulsellum (single/double/multi-tooth)Grasp anterior cervical lip; D&C; grasp submucous myoma; hysterectomySoft pregnant cervix; infectionsLaceration, infection, bleeding
Sim’s uterine soundMeasure cavity length; determine uterine direction; diagnostic differentiationSuspicion of pregnancy; soft uterus (malignancy/infection/molar)Perforation; ascending infection
Hegar’s uterine dilatorsGradual cervical dilatation. Dx: cervical incompetence. Rx: cervical stenosis, dysmenorrhea. Step: prior to D&C/evacuation, VH, before IUD proceduresActive genital infection; pregnant uterus (viable)Perforation; cervical incompetence (most common) → habitual abortion; ascending infection; cervical laceration
Ovum forcepsRemove intact ovum; evacuate uterine contents in D&C; remove IUCD/products
Uterine curette (sharp/blunt)Diagnostic and therapeutic curettage (abnormal bleeding, polyps, etc.)Sepsis; perforation; Asherman’s; bleeding; endometriosis/peritonitis
Urinary catheters (metal, Foley)Induction (Foley mechanical); prevent uterine inertia (1st stage); prevent retained placenta/PPH (3rd stage); diagnose fistulaPressure necrosis; lower tract trauma (e.g., urethral tear)Infections; urethral injury. Metal: sepsis intro, false passage, bladder perforation, urethral shock/fever. Metal advantages vs Foley: less infection/pain
Wooden spatula & cytobrushPap sampling; screen/diagnose cervical cancer at SCJ (transformation zone)Not a true biopsy; it’s a scraping
Laparoscopy set (Veress, trocar/cannula, scope)Minimally invasive access for gynecologic procedures
Amnihook (amniotome)Artificial rupture of membranes
Umbilical cord clampClamp cord postpartum