It is a broad-spectrum antifungal like itraconazole, with good activity against Candida species and many molds.
Adverse Effects
- Hepatotoxicity, rash,
- Drug interactions (potent inhibitor and a substrate of the cytochrome P450 system) that are common with this class,
- Some specific adverse effects:
- renal dysfunction
- Visual effects: such as seeing wavy lines or halos around bright lights
- Central nervous system effects: patients sometimes experience visual and auditory hallucinations.
- Dermatologic: sun sensitivity, and patients should be advised to use sunscreen and avoid excessive sun exposure.