Parasitic Infestations CS-OSPE

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Cutaneous leishmaniasisZ

Working in King Salman forest, developed this lesion from Sandfly bite

diff basal cell carcinoma


Scabies

A 27-year-old man presents with severe itching, that started two weeks ago and has progressively worsened. He reports that his roommates have similar symptoms.

What is the diagnosis?

  • Scabies.

Describe the morphology / Clinical Presentation:

  • Linear burrows, papules, or vesicles with intense pruritus.
  • Pruritic itching which increases at night.
  • Burrows.
  • Commonly involves the axillae, breasts, umbilicus, penis, scrotum, finger webs, and wrists.

Causative organism? / Pathology:

  • Sarcoptes scabiei – scabies mite / Host-specific mite, Sarcoptes scabiei var hominis.

Name two types of this disease? / Types:

  • Classical.
  • Crusted: Usually affects immunocompromised individuals or the elderly.

What other sites should be examined to support the diagnosis?

  • Wrist (flexor aspect)
  • Interdigital web spaces
  • Groin (genital area)
  • Axillae
  • Breasts
  • Umbilicus
  • Penis
  • Scrotum
  • Finger webs

What investigation is done to confirm the diagnosis? / What in-office procedure would best help to confirm the diagnosis of scabies?

  • Skin scraping (mineral oil preparation) + microscopic examination.

What will you see?

  • Mites, eggs, and scybala (feces).

Treatment options? / First line of treatment is?

  • Scabicidal agents:
    • 5% permethrin cream (1% and 5% cream).
      • Must be applied 10 minutes after shampooing and drying hair completely.
      • No hair washing for 24 hours.
    • Sulfur
    • Lindane (gamma benzene hexachloride): Has potential neurotoxicity if abused.
    • Crotamiton (Eurax) 10% cream or lotion.
    • Malathion 0.5% lotion: Protecting against re-infection for 6 weeks.
  • Oral treatment: Ivermectin.
  • Antipruritic agent (e.g., sedating antihistamine).
  • Antimicrobial agent if secondarily infected.

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Pediculosis Capitis

This kid came with itchy scalp, reported one of her family member has the same. A 10-year-old schoolgirl presented with itchy scalp and when you examined her hair you found this picture.

What is the diagnosis?

  • Pediculosis Capitis (head louse) / Head lice (Pediculosis Capitis)

To confirm this diagnosis?

  • Seeing nits on the scalp in clinical exam

What are the clinical presentations?

  • Pruritic eruption on back of scalp and nape.
  • Excoriations & secondary infections (lice dermatitis).
  • Multiple nits present. No lice noted.
  • May also have posterior cervical lymphadenopathy.

What is the pathology?

  • Pediculus humanus capitis.

Treatment options?

  • Permethrin:
    • 1% and 5% cream.
    • Must be applied (10 min) after shampooing and drying hair completely.
    • No hair washing for 24 hours.
  • Pyrethrin
  • Malathion 0.5% lotion:
    • Protecting against re-infection for 6 weeks.
  • Lindane (gamma benzene hexachloride):
    • Has potential neurotoxicity if abused.
  • Crotamiton (Eurax) 10% cream or lotion.
  • Oral Ivermectin

  • Head lice (Pediculosis Capitis)
  • Children
  • Body lice (Pediculosis Corporis)
  • Homeless people and vagrants
  • Public lice (Pediculosis Pubis)
  • STD (partner should be treated)

Bedbug bites

What is the diagnosis?

  • Bedbug bites.

What is the clinical presentation?

  • Edematous papules scattered over the body, some are excoriated.

What is the pathology?

  • Cimex Lectularius.

What investigations are done?

  • Skin scraping (mineral oil preparation).

What is the treatment?

  • Typically resolve within 1-2 weeks.
  • For symptomatic relief, treat with potent topical steroids and antihistamines.