Guidelines for IBS Management

  1. Identify alarming red flag features that indicate the need for further investigations and referral.
  2. Distinguish which aspect of its multi-factorial pathophysiology might prompt the development of IBS in a given patient.
  3. Initiate treatment, including dietary modifications and pharmacological treatment.
  4. Advise patients on the prognosis of the condition.

Diagnostic Criteria

Consider IBS when following symptoms for six months:

  • Abdominal pain or discomfort
  • Bloating
  • Change in bowel habit

Diagnostic Criteria

  • Rome’s Diagnostic criteria.
  • Manning’s Criteria.

Rome’s Diagnostic Criteria

At least 12 weeks history, which need not be consecutive in the last 12 months of abdominal discomfort or pain that has 2 or more of the following:

  • Relieved by defecation.
  • Onset associated with change in stool frequency.
  • Onset associated with change in form of the stool.

Supportive symptoms: Constipation predominant: one or more of

  • Bowel movements less than 3 times a week.
  • Hard or lumpy stools.
  • Straining during a bowel movement.

Diarrhoea predominant: one or more of:

  • More than 3 bowel movements per day.
  • Loose [mushy] or watery stools.
  • Urgency.

General:

  • Feeling of incomplete evacuation.
  • Passing mucus per rectum.
  • Abdominal fullness, bloating or swelling.

Manning’s Criteria

Three or more features should have been present for at least 6 months:

  • Pain relieved by defecation.
  • Pain onset associated with more frequent stools.
  • Looser stools with pain onset.
  • Abdominal distension.
  • Mucus in the stool.
  • A feeling of incomplete evacuation after defecation.

Associated Symptoms

  • In people with IBS in OPD:

    • 25% have depression.
    • 25% have anxiety.
  • Patients with IBS symptoms who do not consult doctors have identical psychological health to the general population.

  • In one study 70% of women IBS sufferers have dysparunia.

  • Stressful life events are associated.

  • Compared with controls, people with IBS are less well educated and have poorer general health.

  • Women: Men = 3:1.

Onset of IBS Symptoms

  • Symptoms usually occur after infection – post-infection, bile salt malabsorption
  • Use of antibiotics
  • Alteration in immune system
  • Emotions, depression, anxiety can affect GIT function
  • Psychological stress can increase GIT symptoms

Subtypes

  • Diarrhoea predominant.
  • Constipation predominant.
  • Pain predominant.

Differential Diagnosis

  • Inflammatory bowel disease.
  • Cancer.
  • Diverticulosis.
  • Endometriosis.

A positive diagnosis, based on Manning’s criteria may provoke less anxiety than extensive tests.

Examination

  • Results should be normal or non-specific.
  • Abdomen and rectal examination.
  • CBC, CRP.
  • No consensus as to whether faecal occult blood (FOBs) or sigmoidoscopy is needed.
  • CBC
  • ESR
  • C-reactive protein (CRP)
  • Antibody testing for coeliac disease
    • Routine testing for celiac disease should be considered in patients with diarrhea-predominant or mixed presentation IBS.

Investigations (Not confirmatory)

  • Ultrasound
  • Rigid/flexible sigmoidoscopy
  • Colonoscopy; barium enema
  • Thyroid function test
  • Faecal ova and parasite test
  • Faecal occult blood