Etomidate
- Mechanism of Action: Facilitates inhibitory neurotransmission by enhancing the function (GABAA) receptors.
- Pharmacokinetics: Effects of a single bolus dose are terminated by redistribution.
- Primary Uses: Induction of anesthesia in patients with cardiovascular problems.
- Advantages: Short acting and potent, with CVS and RS stability, suitable for elderly and shocked patients.
- Adverse Effects:
- Cause nausea and vomiting.
- Adrenal suppression.
- A single dose suppresses adrenal steroid synthesis.
- No analgesic properties.