Pathologic effect of diabetes on blood vessels( Vascular changes)
A- large and medium sized arteries :
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aorta,coronary and cerebral arteries have accelerated atherosclerosis .
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Cerbrovascular: hemorrhage,infarction,memory loss.
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Cardiovascular: angina,heart failure.
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Peripheral vascular disease: ulcer ,gangrene in limbs,foot.
B- small sized arterioles : thickening of their walls due to deposition of hyaline material e.g afferent and efferent arterioloscelrosis of kidney(hypertension).