It is a synthetic nucleoside that have potent antiviral activity against most herpes viruses and is particularly effective against the herpes simplex virus.
Mechanism of action: It is transformed by viral enzyme into triphosphate derivative, which inhibits DNA polymerase necessary for DNA viral replication. This drug shows selective activity against virus only.
Therapeutic uses:Z
- For treatment of genital herpes.
- Treatment of herpes keratoconjunctivitis.
- herps simplex encephalitis.
- herpes zoster.