Family history is important in GIT disorder, outline some examples IBD, Colorectal cancer, Gilbert, Wilson, Haemochromatosis.
IBD
is more common in patients with a family history of either Crohn’s disease or UC
Colorectal cancer
in a first-degree relative increases the risk of colorectal cancer and polyps.
Gilbert’s syndrome
is an autosomal dominant condition
Haemochromatosis and Wilson’s disease
are autosomal recessive disorders
Hereditary haemorrhagic telangiectasias
a rare AD disorder causing vascular dysplasia and results in a tendency for bleeding.
Others:
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Porphyria is a familial disorder presenting with acute abdominal pain,
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Gaucher’s disease: a rare AR inherited lipid disorder, characterized by huge splenomegaly
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Polycystic kidney disease: a common inherited multisystemic and progressive disorder characterized by bilateral enlarged kidneys.