IM

Dr. WAQAR

Introduction

Lymphomas are malignancies arising in the lymphoid tissues, mainly the lymph nodes. There are two important types:

Rapid Fire Questions

  • Which virus is thought to cause Hodgkin’s lymphoma? EBV
  • Which age groups are affected? Bimodal
  • What is the commonest presentation? Node enlargements
  • Are the nodes painful? no
  • What are the three B symptoms? weight loss, fever, nightsweats
  • Does every patient have B symptoms? no
  • What happens after alcohol intake? sometimes increase
  • Which fever pattern is sometimes seen? Pal epstien fever
  • What is the pattern of this fever? cyclic pattern
  • What is the kidney pathology seen in Hodgkin’s lymphoma? minimal change nephrotic syndrome
  • What is the confirmatory diagnostic test & what does it show? Reed sternberg cells
  • Name the four types of classic Hodgkin’s lymphoma.
  • Which investigation is done for staging? PET, CT, MRI
  • How many stages of Hodgkin’s lymphoma are there?
  • Describe stages 1, 2, 3, and 4.
  • Patient has enlarged lymph nodes in the neck and axilla, fever, and weight loss. What stage? S2 2B
  • Enlarged nodes in the axilla and groin. No fever or weight loss. What stage? 3A
  • What is the differential diagnosis of enlarged lymph nodes? lymphadititis
  • What are the two main treatment modalities? chemo, Radio
  • Which chemo regimen is most commonly used? AVBG
  • Name some drugs in this regimen. ABVG, MOPP, Standford V
  • Name some other regimens.
  • What are the two patterns of radiotherapy?
  • Is Hodgkin’s lymphoma a curable cancer?
  • Name three poor prognostic factors.