Selective Serotonin Reuptake Inhibitors (SSRIs)
Selective Serotonin Reuptake Inhibitors (SSRIs)
- Block the presynaptic serotonin reuptake
- Treat both anxiety and depressive sx
- Most common side effects include GI upset, sexual dysfunction (30%+!), anxiety, restlessness, nervousness, insomnia, fatigue.
- Very little risk of cardiotoxicity in overdose
- Can develop a discontinuation syndrome with agitation, nausea, disequilibrium and dysphoria
- (flouxetine ,paroxetine ,escitalopram…..