• Infantile colic is defined as episodes of uncontrollable crying or fussing in an otherwise healthy infant
  • described as paroxysmal and may be characterized by facial grimacing, leg flexion, and passing flatus.
  • Peaks at age of 6 weeks and resolves at age of 3-4 months.
  • It is a diagnosis of exclusion.
  • Fewer than 5% of infants evaluated for excessive crying have an organic etiology.
  • It has been associated with shaken baby syndrome, postpartum depression, parental guilt, and multiple physician visits.

Infantile Colic 2016 ROME IV Criteria

  • Age <5 months when the symptoms start and stop
  • Recurrent and prolonged periods of crying, fussing, or irritability that start and stop without obvious cause and cannot be prevented or resolved by caregivers
  • No evidence of poor weight gain, fever, or illness
  • Caregiver reports of crying/fussing for ≥3 hours per day on ≥3 days/week in a telephone or face-to-face interview
  • Total daily crying confirmed to be ≥3 hours when measured by at least one prospectively kept 24-hour

Full Examination is a Must

***The diagnosis of colic is made only when the physical examination reveals no organic cause for the infant’s excessive crying. ***

A thorough inspection may identify possible sources of pain (differential diagnosis):

  • Skin lesions
  • Corneal abrasions
  • Hair tourniquets
  • Nonaccidental trauma such as bruising or fracture
  • Cow’s milk protein intolerance
  • Gastroesophageal reflux disease (GERD)
  • Maternal substance use including nicotine
  • Poor infant regulation including fatigue, hunger, parental anxiety, and chaotic and disruptive environmental conditions

ApproachY

  • Education (including the natural history and features of colic)
  • Demystification, and a discussion of its natural course
  • Techniques for calming infants include Dr. Harvey Karp’s “5 Ss”:
    1. Swaddling
    2. Side or stomach holding
    3. Soothing noises (such as shushing, singing, or white noise)
    4. Swinging or slow rhythmic movement (such as rocking, walking, or riding in a car)
    5. Sucking on a pacifier