In the intensive care unit, parenteral therapy with closed hemodynamic monitoring is preferred.

Indications of parenteral antihypertensives are:

1- Intracranial hemorrhage. 2- Aortic dissection. 3- Rapidly progressive renal failure. 4- Eclampsia. 5- Hypertensive encephalopathy. 6- In heart failure or myocardial infarction complicating hypertension. 7- Uncomplicated accelerated hypertension and malignant hypertension.