lipoglycopeptide that was modified from vancomycin’s structure but with unique properties that may be advantageous compared with vancomycin, such as improved activity against MRSA that is less susceptible to vancomycin, ((but it is used primarily for patients who do not respond to vancomycin
)). (vancomycin R organisms)
Telavancin is more rapidly bactericidal than Vancomycin because it has
dual mechanism of action:
-
The first as Vancomycin.
-
drug interferes with the cell membrane also, disrupting membrane function.
side effects:
-
Because the core structure of telavancin is essentially Vancomycin, it may cause vancomycin infusion reaction as well.
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Taste disturbances and foamy urine occur with telavancin.