Structural analog of D-alanine
Cycloserine is a broad-spectrum antibiotic that inhibits cell wall synthesis & the growth of many bacteria, including coliforms and mycobacteria
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Exclusively use in strains of Mycobecteria resistant to 1st line anti tuberculous
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Serious dose related nervous toxicity i.e psychosis, tremors, convulsions A wide variety of CNS side effects disturbances may occur, ranging from headache and irritability to depression, convulsions and psychotic states. Its use is limited to tuberculosis that is resistant to other drugs
