Compressive Optic Neuropathy

  • Results from mechanical mass effect secondary to:
    • Tumors (Intracranial, Chiasmal, or Optic Nerve tumors)
    • non-neoplastic lesions:
      • Retrobulbar hemorrhage.
      • Aneurysm.
      • Mucocele.
      • Orbital apex syndrome (thyroid eye disease).

Symptomatology:

  • Slowly progressive process with changes or fluctuations in visual acuity or missing visual field that occur over several months to years.

  • Changes in color vision.

  • Diplopia (double vision), results from interruption of any of the cranial nerves innervating the extraocular muscles (CN III, IV, VI).

  • The optic disc’s appearance may vary greatly depending on the lesion’s location.

  • Early in the compressive disease process, the optic disc may appear normal.

  • Optic disc edema.

  • Atrophic changes (most often due to chronic compression).

  • Presence of optocilliary shunt vessels.

Management:

  • Early and accurate diagnosis with prompt treatment of the underlying cause of the compression is vital to preserve the patient’s vision.
  • Surgical and medical treatments directed at managing the underlying etiology may result in recovery of acuity, fields, and symptoms.