ENT

Differential Diagnosis of Neck Swelling

Definition Any abnormal enlargement, swelling, or growth between the clavicles and mandible.

The Differential Diagnosis of Neck Masses

HISTORY

  • Symptoms (timing is everything)
    • Onset , course ,Duration, recent changes, associated symptoms, sick contacts, recent travel, previous surgery
  • Associated symptoms
    • Fever, dysphagia, weight loss, otalgia, hearing loss, respiratory difficulty, night sweats
  • Past medical/surgical history, allergies, medications, family history
  • Social history - Alcohol, tobacco, drugs, occupation

PHYSICAL

  • Full head and neck exam
    • Skin
    • Ears
    • Mouth/oropharynx
      • Look at the tongue and tonsils
    • Nose and nasopharynx
    • Neck
      • Characterize the mass!
      • Tender, mobile, firm, move with swallowing, overlying skin changes, other lesions
    • Neurologic
      • Full cranial nerve exam

Diagnostic imaging

  • Ultrasound (US)

    • Helpful with children because no sedation needed, inexpensive, avoid ionizing radiation, useful for soft tissue imaging, cystic vs solid, thyroid
    • bad for invasion or bone
  • Computed Tomography (CT)

    • Soft tissue and bone
    • iodinated IV contrast
    • Ideal study for neck mass (CT neck with contrast) – CT without contrast almost useless
  • Magnetic Resonance Imaging (MRI)
    • Superior soft tissue
    • less available, more expensive
    • Often complementary with CT
    • Radionuclide, angiography, plain radiography

Tissue Diagnosis

  • Fine needle aspiration (FNA) biopsy
    • Sens/spec 97%
    • Enhanced with ultrasound
    • Always before an open procedure
    • Cytology and culture
    • If unsuccessful or inconclusive, repeat before an open procedure
    • If failed again, core needle biopsy
    • Open biopsy as last resort
      • Incisional or Excisional biopsy


Clinical Medicine