Hoffman’s sign
Hoffman’s sign is an involuntary flexion movement of the thumb and or index finger when the examiner flicks the fingernail of the middle finger down. This has sensitivity of 59% and a specificity of 49% to screen for upper motor neuron lesion (UMN lesions).
ANKLE AND PATELLAR CLONUS
Clonus: is an abnormal reflex response that involves involuntary and rhythmic muscle contractions. Like other signs of upper motor neuron syndrome clonus indicates some insult to the central rather than peripheral nervous system, so part of its utility as a clinical examination skill is in differentiating the two.
