IMIG/THERA
Mechanism of action:
- V.C of splanchnic blood vessels so, decreasing blood inflow and decrease intravariceal blood flow.
- contraction of esophageal musculature so, collapsing of varices.
- contraction of intestine so, get rid of blood in the bowel.
- V.C of other blood vessels (systemic so, increasing blood pressure , coronary so, producing angina pain, etc….)
- Spasmogenic to other SMF, as uterus leading to its contraction (abortion in pregnant female).
Side effects:
- -Abdominal colic, facial pallor, and bowel evacuation (active drug).
- -PPT myocardial ischemia.
- -abortion in pregnant female.
- -antidiuretic action.