Internal Medicine

  • Very high BP, systolic usually > 180 & diast. > 120
  • BP should be lowered gradually over few hours, to about 110-100 Diastolic.
  • Oral medicines can be given ( but not TAHT-AL LISAAN !
  • HTN emergency needs ICU admission & i.v. meds.
    • nitroglycerin * nitroprusside
    • i.v. hydralazine * Nicardipine * labetolol
  • Don’t “reduce” the BP quickly. Reduce by 10% in the first hour, then slowly. Normalisation can occur over few days.
  • Don’t give sublingual medicines. It will cause sudden drop in BP can cause ischemia to the brain
  • If not treated timely, hypertensive crisis can cause permanent end organ damage.


Therapeutics

THERA HTN RENAL STENSOSIS

Very high BP, systolic usually > 180 & diast. > 120

  • BP should be lowered gradually over few hours, to about 110-100 Diastolic.
  • Oral medicines can be given ( but not TAHT-AL LISAAN !)

HTN emergency needs ICU admission & i.v. meds.

  • nitroglycerin   
  • nitroprusside 
  • i.v. hydralazine
  • Nicardipine
  • labetolol

Note

  • Dont “reduce” the BP quickly. Reduce by 10% in the first hour, then slowly. Normalisation can occur over few days.
  • Don’t give sublingual medicines. It will cause sudden drop in BP ⇒ can cause ischemia to the brain
  • If not treated timely, hypertensive crisis can cause permanent end organ damage.

Pathological Complications

  • Rapidly progressive end organ damage
  • May complicate any type of HPTN
  • Artery necrosis with thrombosis
  • Rapidly developing renal failure
  • Hypertensive encephalopathy
  • Left ventricular failure