Functional Neuroimaging

Principles in diagnosis of epilepsy

  • When a region of brain generates seizure, its regional blood flow, metabolic rate and glucose utilization increase
  • After seizure, there is a decline to below the level of other brain regions throughout the interictal period

Functional Neuroimaging

  • Modalities available: â–  Positron Emission Tomography (PET) â–  Single Photon Emission Computerized Tomography (SPECT) â–  Functional Magnetic Resonance Imaging (fMRI)
  • Mostly used in: â–  Planning epilepsy surgery â–  Identifying epileptogenic region â–  Localizing brain function