Vasodilator therapy
Direct vasodilators
I. Mixed vasodilators (Recommended - best long term) II. Venodilators (Tolerance develop - worsening HF) Ill. Arteriolar vasodilators (Not Recommended)
Other Therapies
- Diuretics Best FIRST LINE Furo (acute) -/+ Thia (chronic) & Lactones
- Beta-blockers; generally not advisable, unless pheochromocytoma, thyrotoxicosis, and increased sympathetic overactivity - prevention or partially reverse progressive left ventricular diltation
- Nesiritide - Dyspnea at rest HF - Unstable
- Anticoagulants - Afib - Thromboembolisms, Thrombus
- Antiarrhythmics As amiodarone that has little negative inotropic effect can be used in ventricular arrhythmia
Positive inotropic drugs:
''''Not generally advisable to use long term - there are some exceptions ''''
- Cardiac Glycosides - Ca2+ Influx
- Dopamine and dobutamine (used for short term only ). - B1 Stimulation
- Phosphodiesterase Inhibitors (PDE): amrinone and milrinone.