Omar Alaidaroos

Diseases of small bowel

Anatomy

  • Small bowel extends from the pylorus to the ileocaecal junction.
  • 2.75 -10.49 m long, & 2.5–3 cm in diameter.
  • The surface area of its mucosa is 30 square meter
  • It receives blood supply from the coeliac trunk, & superior mesenteric artery
  • 3 distinct regions – the duodenum, jejunum, & ileum.
  • Ileocecal sphincter – Transition between small and large intestine

Function:

  • Absorption of nutrients, & minerals  from food, using small finger-like protrusions called villi.
  • (sugars, amino acids, and fatty acids)
  • Chemical digestion
  • Absorbed in Duodenum → Fe, Ca++, B2, B6.
  • Absorbed in Jejunum → B1 & B9.
  • Absorbed in terminal ileum → B12, bile salts, Vits ADEK

Parts of small intestine

Duodenum:

  • Shortest part (20-25 cm) in length, & preparation for absorption begins.
  • Shaped like a “C”. It surrounds the head of the pancreas.
  • It has 4 parts
  • Receives bile through CBD, and pancreatic juice  through
  • the pancreatic duct, controlled by the sphincter of Odd
  • It has Bruner’s glands, which empty into the intestinal glands, secrete an alkaline fluid composed of mucin, which exerts a physiologic anti-acid function by coating the duodenal epithelium, therefore protecting it from the acid chyme of the stomach.

Jejunum:

  • Is the midsection of the small bowel, connecting the duodenum to the ileum.
  • It is about 2.5 m long
  • Contains the plicae circulares, & villi  that increase its surface area.
  • The suspensory muscle of the duodenum marks the division between the duodenum and the jejunum.

Ileum:

  • It is about 3 m long and contains villi like the jejunum.
  • It has Peyer’s patches (Aggregated lymphoid nodules)
  • It joins to the cecum of the large bowel at the ileocecal junction

Peyer’s Patch