Median Nerve Injury

Anatomical Course and Innervation

Course Distribution

  • Upper arm: Lateral cord, Medial cord
  • Forearm: Median nerve, Flexor-pronator muscle group (Pronator teres, Palmaris longus, Flexor carpi radialis, Flexor digitorum superficialis, Flexor pollicis longus), Articular rami (2), Flexor digitorum profundus (radial portion)
  • Wrist/Hand: Thenar muscles (Abductor pollicis brevis, Opponens pollicis, Flexor pollicis brevis (superficial head)), First and second lumbricales, Pronator quadratus, Anastomosis with ulnar nerve

Level of Injury and Clinical Manifestations

High Median Nerve Injury (Above Elbow)

Loss of function:

  • Pronation of forearm
  • Wrist flexion
  • Index & middle finger flexion
  • Thumb flexion
  • Opposition
  • Sensory loss

Low Median Nerve Injury (Below Elbow)

Loss of function:

  • Thumb opposition (abductor pollicis brevis)
  • Sensory loss

Characteristic Deformity: “Ape Hand”

Features:

  • Ape-like hand appearance
  • Thenar muscles wasted
  • Thumb is adducted (unopposed)

Diagram illustrating the “Ape-hand” deformity in median nerve lesion, showing:

  • Unopposed thumb
  • Thenar atrophy

Sensory Distribution

Characteristic sensory loss:

  • Lateral 3.5 fingers on palmar side
  • Distal phalanges of lateral 3.5 fingers on dorsal surface
  • “Area of isolated supply” on the thumb, index, and middle fingers

Anterior Interosseous Nerve Syndrome

Special clinical signs:

  • OK sign (inability to make OK gesture)
  • Pointing index sign