Renin-Angiotensin-Aldosterone Mechanism
- Low blood volume and renal perfusion trigger the release of renin from the kidney.
- Renin converts angiotensinogen to angiotensin I.
- ACE converts angiotensin I to angiotensin II.
- Aldosterone from the adrenal cortex promotes reabsorption of sodium and water and excretion of potassium.
The renin-angiotensin-aldosterone system is activated by high plasma osmolarity, low blood volume, low blood pressure, and stimulation of the sympathetic nervous system.
2-Aldosterone
End product of RAAS
It increases the expression of ATPase pumps in the nephron that causes an increase in water reabsorption through sodium cotransport.
The renin –angiotensin aldosterone system is activated by high plasma osmolarity, low blood volume, low blood pressure, and stimulation of the sympathetic nervous system.
