Gangrene

It is macroscopic death of tissue in situ with or without putrefaction.

FeatureDry gangreneWet gangrene
AppearanceDry, shriveled, mummifiedEdematous, putrified and discoloured
CauseOccurs due to slow and gradual loss of blood supplyOccurs due to sudden loss of blood supply
InfectionInfection not presentInfection present (offensive odor)
SymptomsCold temp., dull aching pain
Skin changes colour to dark brown → dark purplish → completely dark
Offensive odor
Swollen, red and warm
DemarcationClear line of demarcation is presentVague/ No line of demarcation
ExtensionNo proximal extensionProximal extension
AmputationLimited amputationHigh amputation

Gangrene typically refers to necrosis with putrefaction of tissue, the tissue will characteristically appear black.

There is Two types: wet and dry types.

  • In “wet type”, the process is complicated by cellular destruction by bacterial enzymes.
  • In “dry type”, cellular structure is maintained. It can be progress from (dry) to (wet). Best exemplified in peripheral vascular disease where an initial patch of dry gangrene progresses to wet gangrene as a result of super-added infection.

Black discoloration involving distal medially foor represent gang, no obvious discharge, foot is edematous, edematous, no hair, muscle wasting…