| Antibiootic | MOA | Spectrum +++ | Uses | Side Effects |
|---|
| Bacitracin | Prevents cell wall synthesis | Gram +ve cocci Few Gram -ve | Topical combination | Nephrotoxic |
| Vancomycin | Inhibit cell wall synthesis | Gram +ve only | Drug of choice in pseudomembranous colitis (superinfection by antibiotics MRSA) | ototoxicity &Red neck syndrome: Chills, Fever, Maculopapular rash (head and upper thorax) due to histamine release. |
| POLYMYXINS | | Facultative Gram -ve (P. aeruginosa and Coliform) | Combination to reduce catheter associated infection. Topical combination | Nephrotoxic Neurotoxic Neuromuscular blockade |
| Sodium fusidate (Fucidin) | Inhibits 50s Ribosomal subunit | Gram +ve Gram -ve diplococci | Acne | |