HF

Nesiritide is used intravenously to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.

Nesiritide has beneficial vasodilatory, natriuretic, diuretic and neurohormonal effects through the negative regulation of the renin-angiotensin-aldosterone system.