Angiotensin II receptor blockers (ARBs) (Losartan, valsartan, candesartan, eprosartan, telmisartan)
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They selectively block AT1 receptors.
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They have no effect on bradykinin metabolism.
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They have the potential for more complete inhibition of Ang-2 action compared with ACE inhibitors because there are non-ACE enzymes (cathepsin and chymase) that can convert Ang-1 into Ang-2.
The adverse effects and contraindications
are similar to those described for ACE inhibitors but cough and angioedema are less common than with ACE inhibitors.