Necrotizing fasciitis: 

Soft tissue infection, in which there is destruction and necrosis of tissue in skin, subcutaneous tissue, muscles. Usually follows abdominal surgery or trauma.

Caused by:

  • Infection with group A Streptococcus, commonly known as “flesh-eating bacteria” 

Others include:

  • Aeromonas hydrophila
  • Clostridium
  • E. coli
  • Klebsiella
  • Staphylococcus aureus

Immuno - compromised [e.g. Diabetics and IV drug addicts] are more susceptible.

Common sites: abdominal wall, perineum and limbs.

Starts as cellulitis with early systemic toxicity. It is characterized by non-blanching erythema, with blisters and frank necrosis of the skin. No definitive margins

TREATMENT:
Extensive surgical debridement of the affected area, in combination with high dose broad spectrum is the appropriate Rx till C/S result.

Fourniers gangrene: is defined as a polymicrobial necrotizing fasciitis of the perineal, perianal, or genital areas