Postpartum Pyrexia

Presented by: Abduelah Almarzooq, Faisal Alkharji, Abdulmohsen Alhussain, Nawaf Alsaggaf. Supervised by: DR. Mona Ahmed

OVERVIEW

  • Define postpartum pyrexia
  • Identify the risk factors
  • Conduct a detailed history and physical examination
  • Formulate a differential diagnosis
  • Plan appropriate investigations
  • Propose a management plan
  • Reference

Definition

Postpartum pyrexia is defined as a maternal temperature greater than 38.0 °C (100.4 °F) occurring on any two of the first ten days following delivery, excluding the first 24 hours postpartum.

Risk Factors

  • Caesarean section (C-section).
  • Premature rupture of membranes (PROM).
  • Multiple vaginal examinations during labor.
  • Manual removal of the placenta.
  • Prolonged labor.
  • Other contributors:
    • Urinary tract infections.
    • Surgical incision infections.

History & Physical Examination

History:

  • Onset, duration, and pattern of fever.
  • Associated symptoms: foul-smelling lochia, pelvic pain, dysuria, breast pain, wound discharge.
  • Obstetric history (delivery type, complications).

Examination:

  • Vital signs.
  • Uterus: tenderness, subinvolution, abnormal lochia.
  • Perineum/cesarean wound: erythema, discharge.
  • Breasts: engorgement, mastitis, abscess.
  • Urinary system: suprapubic tenderness.

Differential Diagnosis

The 7 Ws of Postpartum Pyrexia

Womb, Wound, Water

  1. Womb (Endomyometritis)

    • What: Most common cause; a uterine infection, esp. post C-section.
    • When: Days 3-7.
    • Signs: Uterine tenderness, foul-smelling lochia. An early, high fever can be a red flag.
  2. Wound (Infection)

    • What: Infection at a C-section, episiotomy, or laceration site.
    • When: Days 4-7.
    • Signs: Localized redness, warmth, purulent drainage.
  3. Water (UTI)

    • What: Urinary tract infection, often from catheterization.
    • When: Days 1-3.
    • Signs: Painful urination, frequency. Flank pain suggests kidney infection.

Weaning & Wind

  1. Weaning (Mastitis/Engorgement)

    • What: Breast issues from milk stasis.
    • Engorgement (Days 2-3): Low-grade fever.
    • Infectious Mastitis (After Day 7): High fever, chills, and a tender, red wedge on one breast.
  2. Wind (Pulmonary Issues)

    • What: Atelectasis (collapsed lung) or pneumonia, esp. after general anesthesia.
    • When: First 72 hours.
    • Signs: Cough and shortness of breath.

Walking & Wonder Drugs

  1. Walking (Thromboembolism)

    • What: Blood clots; a serious postpartum concern.
    • DVT (Days 5-10): Unilateral leg pain and swelling.
    • Septic Pelvic Thrombophlebitis: Rare; fever persists despite antibiotics.
  2. Wonder Drugs (Drug Fever)

    • What: A diagnosis of exclusion from a medication reaction.
    • When: About a week after starting a new drug.
    • Signs: Fever resolves when the drug is stopped.

Other Considerations

  • Viral Infections: Common illnesses (e.g., influenza, gastroenteritis).
  • Malaria: Crucial with travel history to endemic areas.
  • Rare Conditions: Such as a thyroid storm.

Investigations

  • CBC
  • ESR/CRP
  • Blood cultures
  • Urinalysis and urine culture
  • High vaginal swab and endocervical swab
  • Pelvic ultrasound (to rule out retained products or abscess)

Management

1. General Measures

  • Stabilize (ABCs, IV access, fluids if unstable).
  • Antipyretics (e.g., paracetamol).
  • Adequate hydration.
  • Encourage early ambulation.
  • Continue breastfeeding unless contraindicated.

2. Antibiotics

  • Endometritis (most common):
    • IV Clindamycin + Gentamicin until afebrile 24–48h, Add Ampicillin if Enterococcus suspected.
  • Wound infection:
    • IV broad-spectrum
      • (Co-amoxiclav or Cefazolin + Metronidazole).
  • UTI:
    • IV Ceftriaxone
  • Mastitis/Breast abscess:
    • Oral Dicloxacillin/Flucloxacillin

3. Source control

  • Drain abscesses (breast, wound).
  • Debride necrotic/infected tissue.

4. Monitoring & Follow-Up

  • Monitor vitals, urine output, and labs.
  • Tailor antibiotics once cultures return.

REFERENCE

  • AMBOSS
  • Hacker & Moore’s ESSENTIALS OF OBSTETRICS & GYNECOLOGY